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[特立帕肽——骨质疏松症治疗的新价值:治疗指南]

[Teriparatide--new value in osteoporosis treatment: treatment guidelines].

作者信息

Korsić Mirko, Kastelan Darko

机构信息

Zavod za endokrinologiju i bolesti metabolizma, Klinika za unutarnje bolesti, Klinicki bolnicki centar Zagreb, Kispatićeva 12, 10000 Zagreb.

出版信息

Reumatizam. 2006;53(2):77-81.

Abstract

Osteoporosis has become global health issue due to the longer life-cycle and increased percentage of older people in population. The great improvement was done in the treatment of postmenopausal osteoporosis. By the mechanism of action, drugs for osteoporosis treatment are antiresorptives and osteoanabolics. Teriparatide is an osteoanabolic drug that stimulates bone turnover and building of a new bone, indicated for treatment of women in postmenopause with multiple osteoporotic fractures.

摘要

由于人口寿命延长和老年人比例增加,骨质疏松症已成为全球性健康问题。绝经后骨质疏松症的治疗取得了巨大进展。从作用机制来看,用于治疗骨质疏松症的药物分为抗骨吸收药物和骨合成代谢药物。特立帕肽是一种骨合成代谢药物,可刺激骨转换和新骨生成,适用于治疗患有多发性骨质疏松性骨折的绝经后女性。

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