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[食管癌术后脑转移:4例报告]

[Postoperative brain metastasis from esophageal carcinomas: report of 4 cases].

作者信息

Kaneko T, Hirao M, Shimada M, Takayama T, Iwazawa T, Murata K, Inoue M, Terashima T, Mizunoya S, Okagawa K

机构信息

Department of Surgery, Kinki Central Hospital, Mutual Aid Association of Public School Teachers.

出版信息

Kyobu Geka. 1991 Nov;44(12):1013-7.

PMID:1758102
Abstract

Out of 83 cases received resection of primary esophageal lesion, 4 patients were affected by metastatic brain tumor which was reported to rarely occur. All 4 patients had symptoms of central nervous system. Three of them were diagnosed by CT and the other one at autopsy. All of the primary esophageal tumors were advanced and of histological stage III or IV. They located in the middle or lower thoracic esophagus. Brain tumor of one case was removed and this case was of progression free at the last presentation. The other 3 cases were not received resection of metastatic brain tumors and died. All of 3 were autopsied and two of them had no metastasis in the lung. Therefore, it was considered that these hematogenic metastases were not through lung filtrations but through other routes, which Batson O. V. experimentally proved and designated as vertebral vein system in 1940. It is concluded that aggressive surgical intervention to metastatic brain tumors was beneficial with regard to prognosis for cases without other metastatic lesions.

摘要

在83例接受原发性食管病变切除术的患者中,有4例发生了转移性脑肿瘤,据报道这种情况很少见。所有4例患者都有中枢神经系统症状。其中3例通过CT诊断,另1例通过尸检诊断。所有原发性食管肿瘤均为晚期,组织学分期为III期或IV期。它们位于胸段食管中下段。1例患者的脑肿瘤被切除,该病例在最后一次就诊时无疾病进展。另外3例未接受转移性脑肿瘤切除术并死亡。所有3例均进行了尸检,其中2例肺部无转移。因此,认为这些血行转移不是通过肺过滤,而是通过其他途径,1940年Batson O.V.通过实验证明并将其命名为椎静脉系统。结论是,对于没有其他转移病变的病例,对转移性脑肿瘤进行积极的手术干预对预后有益。

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