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[对患结核病小儿患者接触者的调查]

[The investigation of the contacts of the tuberculous pediatric patient].

作者信息

Casanova Matutano C, González Monte C, Pérez Martín M, Piqueras Altabella R, Estellés Dasí C, Morera Llorca M

机构信息

Servicio de Pediatría, Hospital de Sagunto, Puerto de Sagunto, Valencia.

出版信息

Med Clin (Barc). 1991 Oct 19;97(13):486-90.

PMID:1758205
Abstract

BACKGROUND

Results of contacts investigation of tuberculous pediatric patients, usually non-infectious, are shown. Their relationship to the clinical situation on index case and the intimacy of exposure is analyzed.

METHODS

714 contacts of 111 pediatric cases (53 category II and 58 category III, according to the American Thoracic Society classification). The tuberculin skin test with 2 units of PPD-RT23 was used to identify the infected persons. Chest radiography, sputum smear and culture examination were used to diagnose current pulmonary disease. According to the intimacy of exposure to index case, contacts were defined as household, close or sporadic contacts. The possible association with clinical situation of index case and intimacy of exposure was analyzed.

RESULTS

41 new cases of tuberculosis were detected, 7 of them were infectious. Prevalence of tuberculous infection among contacts was 44%. Quimioprofilaxis was indicated to 126 contacts. The prevalences of infection and disease according to clinical situation and degree of contact did not differ significantly.

CONCLUSIONS

it is advisable to investigate the contacts of tuberculous pediatric patients, even in cases of tuberculous infection without disease; the investigation must include close and sporadic contacts.

摘要

背景

展示了对通常无传染性的结核患儿接触者调查的结果。分析了他们与索引病例临床情况及接触密切程度的关系。

方法

111例儿科病例的714名接触者(根据美国胸科学会分类,53例为II类,58例为III类)。采用2单位PPD-RT23进行结核菌素皮肤试验以识别感染者。胸部X线摄影、痰涂片和培养检查用于诊断当前的肺部疾病。根据与索引病例接触的密切程度,接触者被定义为家庭接触者、密切接触者或散在接触者。分析了与索引病例临床情况及接触密切程度的可能关联。

结果

检测到41例新的结核病例,其中7例具有传染性。接触者中结核感染率为44%。对126名接触者进行了化学预防。根据临床情况和接触程度,感染率和发病率无显著差异。

结论

即使在无疾病的结核感染病例中,也建议对结核患儿的接触者进行调查;调查必须包括密切接触者和散在接触者。

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