Le Gall O, Sanfaçon H, Ikegami M, Iwanami T, Jones T, Karasev A, Lehto K, Wellink J, Wetzel T, Yoshikawa N
INRA Bordeaux-Aquitaine and Université Victor Segalen, Villenave d'Ornon, France.
Arch Virol. 2007;152(9):1767-74. doi: 10.1007/s00705-007-1015-0. Epub 2007 Jun 22.
The genus Nepovirus (family Comoviridae) was known both for a good level of homogeneity and for the presence of atypical members. In particular, the atypical members of the genus differed by the number of capsid protein (CP) subunits. While typical nepoviruses have a single CP subunit with three structural domains, atypical nepoviruses have either three small CP subunits, probably corresponding to the three individual domains, or a large and a small subunit, probably containing two and one structural domains, respectively. These differences are corroborated by hierarchical clustering based on sequences derived from both genomic RNAs. Therefore, these atypical viruses are now classified in two distinct genera, Cheravirus (three CP subunits; type species Cherry rasp leaf virus) and Sadwavirus (two CP subunits; type species Satsuma dwarf virus).
线虫传多面体病毒属（双分病毒科）以高度的同源性和非典型成员的存在而闻名。特别是，该属的非典型成员在衣壳蛋白（CP）亚基数量上有所不同。典型的线虫传多面体病毒有一个带有三个结构域的单一CP亚基，而非典型的线虫传多面体病毒要么有三个小的CP亚基，可能对应于三个单独的结构域，要么有一个大亚基和一个小亚基，可能分别包含两个和一个结构域。基于来自两种基因组RNA的序列进行的层次聚类证实了这些差异。因此，这些非典型病毒现在被分为两个不同的属，樱桃病毒属（三个CP亚基；模式种樱桃锉叶病毒）和萨德瓦病毒属（两个CP亚基；模式种温州蜜柑萎缩病毒）。
