Dong Jian-Ping, Sun Wei-Yi, Wang Shun, Wu Zhi-Quan, Liu Fei
Section of Acupuncture and Moxibustion, Heilongjiang Provincial Academy of TCM, Harbin 150036, China.
Zhongguo Zhen Jiu. 2007 Apr;27(4):241-4.
To observe clinical therapeutic effect of head point-through-point electroacupuncture (EA) on poststroke depression (PSD) and to study the mechanism.
One hundred and eight cases of PSD were randomly divided into a point-through-point EA group (n = 38), a non point-through-point group (n = 36) and a western medicine group (n = 34). After treatment of 28 days, their therapeutic effects, scores of HAMD depression scale and SDS self-rating scale, and plasma 5-HT contents were compared before and after treatment among the 3 groups.
The effective rate of 86.84% in the point-through-point EA group was better than 63.89% in the non point-through-point group and 67.65% in the western medicine group (P < 0.05 or P < 0.01). Plasma 5-HT content in the point-through-point EA group increased significantly, with a very significant difference as compared with that of the non point-through-point group (P < 0.01).
Head point-through-point therapy can obviously increase plasma 5-HT content of the patient with PSD, so as to cure poststroke depression, with a better therapeutic effect than other two groups.
观察头部透穴电针治疗脑卒中后抑郁(PSD)的临床疗效并探讨其机制。
将108例PSD患者随机分为透穴电针组(n = 38)、非透穴组(n = 36)和西药组(n = 34)。治疗28天后,比较3组治疗前后的疗效、汉密尔顿抑郁量表(HAMD)评分、抑郁自评量表(SDS)评分及血浆5-羟色胺(5-HT)含量。
透穴电针组有效率为86.84%,优于非透穴组的63.89%和西药组的67.65%(P < 0.05或P < 0.01)。透穴电针组血浆5-HT含量显著升高,与非透穴组比较差异非常显著(P < 0.01)。
头部透穴疗法能明显提高PSD患者血浆5-HT含量,从而治愈脑卒中后抑郁,疗效优于其他两组。