Xu Lei, Wang Ling-Ling
The Second Clinical Medical College of Nanjing University of CM, Nanjing 210029, Jiangsu Province, China.
Zhongguo Zhen Jiu. 2011 Sep;31(9):779-82.
To evaluate the clinical therapeutic effect of depression treated by acupuncture and electroacupuncture combined with western medicine.
Seventy-five patients were randomly divided into 3 groups. In control group, 30 cases were treated by SSRI with oral administration; in observation group 1, 25 cases were treated by acupuncture therapy combined with SSRI, and Shenting (GV 24), Baihui (GV 20), Dazhui (GV 14), Shendao (GV 11) and Zhiyang (GV 9) etc. were selected with regulating qi needling method; in observation group 2, same acupoints were selected with routine needling method, and 20 cases were treated by electroacupuncture therapy combined with SSRI, Baihui (GV 20) and Yintang (EX-HN 3) etc. were treated by electroacupuncture. The clinical therapeutic effects and Hamilton Depression Scale scores were evaluated after 1, 2, 4 and 6 weeks treatment.
The total effective rates of observation group 1 and 2 were 100.0%, superior to that of 73.3% in control group (both P < 0.05). The total scores of HAMD on each time point dropped, and there were significant differences compard with those before treatment in 3 groups (P < 0.01, P < 0.05); the total scores of HAMD after 1, 2 and 4 weeks improved more obviously than that in control group (P < 0.01, P < 0.05), and there was no significant difference among groups after 6 weeks (all P > 0.05). After one week treatment, the comparison of total scores of HAMD in observation group land 2 indicated significant differences (P < 0.05); after 2, 4 and 6 weeks treatment, there were no significant differences between groups (all P > 0.05).
The acupuncture therapy and electroacupuncture combined with western medicine for treating depression have better effects than medicine treatment; and there is no obvious difference between acupuncture therapy and electroacupuncture therapy, however, the effect works fast by electroacupuncture.
评价针刺、电针结合西药治疗抑郁症的临床疗效。
将75例患者随机分为3组。对照组30例采用口服SSRI治疗;观察组1共25例,采用针刺疗法结合SSRI治疗,选取神庭(GV 24)、百会(GV 20)、大椎(GV 14)、神道(GV 11)、至阳(GV 9)等穴位,采用调气针法;观察组2共20例,采用常规针法选取相同穴位,采用电针疗法结合SSRI治疗,对百会(GV 20)、印堂(EX-HN 3)等进行电针治疗。治疗1、2、4、6周后评估临床疗效及汉密尔顿抑郁量表评分。
观察组1和观察组2的总有效率均为100.0%,优于对照组的73.3%(P均<0.05)。3组各时间点汉密尔顿抑郁量表总分均下降,与治疗前比较差异有统计学意义(P<0.01,P<0.05);观察组1和观察组2治疗1、2、4周后的汉密尔顿抑郁量表总分改善较对照组更明显(P<0.01,P<0.05),6周后组间比较差异无统计学意义(P均>0.05)。治疗1周后,观察组1和观察组2的汉密尔顿抑郁量表总分比较差异有统计学意义(P<0.05);治疗2、4、6周后,组间比较差异无统计学意义(P均>0.05)。
针刺、电针结合西药治疗抑郁症的效果优于单纯药物治疗;针刺疗法与电针疗法之间无明显差异,但电针起效更快。