van Bruggen A C, Mooij J J, Journée H L
Department of Neurosurgery, University Hospital Groningen, The Netherlands.
Neurosurgery. 1991 Dec;29(6):845-9. doi: 10.1097/00006123-199112000-00007.
A new recording method for the acoustical detection of intracranial aneurysms is presented. A study examining the capability of the method to discriminate between patients with an aneurysm and control patients by a simple, objective parameter is reported. Sound signals were recorded over the eyes, and a real-time spectral analysis was performed on these signals. For this study, recordings performed on 26 patients with an aneurysm were compared with recordings on 26 age- and sex-matched control patients without intracerebral abnormalities. As a result of measures taken to reduce artifacts and to improve the signal-to-noise ratio, the measurements were performed reliably, with little inconvenience for the patients; all measurements could be used for analysis. The power spectra measured in the control patients showed a typical, smoothly descending pattern; those measured in the aneurysm patients clearly differed from this pattern, showing peaks of varying width, height, and dominant frequency. For the objective judgment of the power spectra, the power median is introduced. The sensitivity and specificity of this parameter were determined. Possible methods to improve the results will be discussed.
提出了一种用于颅内动脉瘤声学检测的新记录方法。报道了一项通过简单、客观参数研究该方法区分动脉瘤患者和对照患者能力的研究。在眼睛上方记录声音信号，并对这些信号进行实时频谱分析。在本研究中，将26例动脉瘤患者的记录与26例年龄和性别匹配、无脑内异常的对照患者的记录进行了比较。由于采取了减少伪影和提高信噪比的措施，测量得以可靠地进行，对患者造成的不便很小；所有测量结果均可用于分析。对照患者测量的功率谱显示出典型的、平滑下降的模式；动脉瘤患者测量的功率谱明显不同于该模式，显示出宽度、高度和主频各异的峰值。为了对功率谱进行客观判断，引入了功率中位数。确定了该参数的敏感性和特异性。将讨论改善结果的可能方法。
