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在接受抗缺血事件的抗凝和抗血小板治疗后立即出现蛛网膜下腔出血的后下小脑动脉动脉瘤解剖。

Dissecting posterior inferior cerebellar artery aneurysm presenting with subarachnoid hemorrhage right after anticoagulant and antiplatelet therapy against ischemic event.

作者信息

Takumi Ichiro, Mizunari Takayuki, Mishina Masahiro, Fukuchi Takaharu, Nomura Ryutaro, Umeoka Katsuya, Kobayashi Shiro, Teramoto Akira

机构信息

Department of Neurosurgery, Neurological Institute, Chiba Hokuso Hospital, Nippon Medical School, Chiba 270-1694, Japan.

出版信息

Surg Neurol. 2007 Jul;68(1):103-7; discussion 107. doi: 10.1016/j.surneu.2006.08.063.

Abstract

BACKGROUND

Dissecting aneurysms with initial ischemic manifestations may present with subsequent subarachnoid hemorrhage (SAH), and their treatment is controversial. This is a case report that illustrates the dilemma when dealing with an immediate post-SAH period dissecting posterior inferior cerebellar artery (PICA) aneurysm initially presenting with an ischemic event.

METHODS

We present a 57-year-old man with a dissecting PICA aneurysm who had SAH right after anticoagulant and antiplatelet therapy for cerebral infarction. The aneurysm was not detected by magnetic resonance angiography performed at the time of admission.

RESULTS

On admission, he was treated with both anticoagulant and antiplatelet therapy. After the SAH episode, he underwent emergent resection of the dissecting aneurysm and left OA-PICA anastomosis.

CONCLUSION

If hemorrhagic transformation occurs at the site of an ischemic dissecting aneurysm, surgical or endovascular intervention should be considered immediately. Although the optimal treatment of dissecting aneurysms with ischemic onset remains controversial, anticoagulant and antiplatelet therapy should not be rejected out of hand.

摘要

背景

最初表现为缺血症状的夹层动脉瘤可能随后出现蛛网膜下腔出血(SAH),其治疗存在争议。这是一例病例报告,阐述了在处理最初表现为缺血事件的SAH后即刻夹层小脑后下动脉(PICA)动脉瘤时所面临的困境。

方法

我们报告一名57岁男性,患有夹层PICA动脉瘤,在接受脑梗死抗凝和抗血小板治疗后随即发生SAH。入院时进行的磁共振血管造影未检测到该动脉瘤。

结果

入院时,他接受了抗凝和抗血小板治疗。SAH发作后,他接受了夹层动脉瘤紧急切除术和左枕动脉-小脑后下动脉吻合术。

结论

如果缺血性夹层动脉瘤部位发生出血转化,应立即考虑手术或血管内介入治疗。尽管缺血性发作的夹层动脉瘤的最佳治疗仍存在争议,但不应轻易拒绝抗凝和抗血小板治疗。

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