Ratliff D A, Puttick M, Libertiny G, Hicks R C J, Earby L E, Richards T
Vascular Unit, Department of Surgery, Northampton General Hospital NHS Trust, Billing Road, Northampton NN1 5BD, UK.
Eur J Vasc Endovasc Surg. 2007 Sep;34(3):322-6. doi: 10.1016/j.ejvs.2007.04.014. Epub 2007 Jun 22.
To assess the long-term outcome of supervised exercise training for intermittent claudication.
A prospective study was undertaken of all patients referred to a single centre with intermittent claudication (>46 m). Patients underwent supervised exercise training twice weekly for 10 weeks, with regular follow-up to 3 years. Actual Claudication Distance (ACD), Maximum Walking Distance (MWD) and ankle-brachial pressure indices (ABPI) were measured.
In 202 patients the initial median ACD and MWD were 112 m and 197 m. Following exercise therapy both the median ACD and MWD increased to 266 m and 477 m at three months, increases of 237% and 242% respectively (p<0.001). At three years the median ACD and MWD were 250 m and 372 m, increases of 223% and 188% respectively (p<0.001). There was no significant change in ACD or MWD at 3 months compared to 1, 2 or 3 years. ABPI remained unchanged throughout.
Supervised exercise training has long term benefit in patients with intermittent claudication. Results seen at 12 weeks are sustained at three years.
评估间歇性跛行患者接受有监督的运动训练的长期效果。
对所有转诊至单一中心的间歇性跛行(>46米)患者进行前瞻性研究。患者每周接受两次有监督的运动训练,为期10周,并定期随访3年。测量实际跛行距离(ACD)、最大行走距离(MWD)和踝臂压力指数(ABPI)。
202例患者的初始中位ACD和MWD分别为112米和197米。运动治疗后,三个月时中位ACD和MWD分别增加到266米和477米,分别增加了237%和242%(p<0.001)。三年时,中位ACD和MWD分别为250米和372米,分别增加了223%和188%(p<0.001)。与1年、2年或3年相比,3个月时ACD或MWD无显著变化。ABPI在整个过程中保持不变。
有监督的运动训练对间歇性跛行患者有长期益处。12周时观察到的结果在三年时得以维持。