Teranishi Kohsuke, Yamamoto Takuji, Nakao Yasuaki, Osada Hideo, Wada Ryo, Mori Kentaro
Department of Neurosurgery, Juntendo University Shizuoka Hospital, Izunokuni, Shizouka, Japan.
Neurol Med Chir (Tokyo). 2007 Jun;47(6):269-72. doi: 10.2176/nmc.47.269.
A 61-year-old male presented with a recurrent solitary fibrous tumor (SFT) arising from the falx cerebri with intraventricular extension manifesting as nausea and vomiting. Magnetic resonance imaging showed the heterogeneously enhanced tumor in the falx, which extended to the bilateral lateral ventricles and the third ventricle. Total tumor removal was performed via the bifrontal interhemispheric approach. Histological examination showed mostly spindle cells with rich intercellular fibers. Immunohistochemical examination showed strong staining for CD34 in the cytoplasm but no staining for epithelial membrane antigen. Reexamination of the two previous tumor specimens, previously identified as fibrous meningioma, found SFT. The differential diagnosis of SFT in the central nervous system from fibrous meningioma and hemangiopericytoma requires immunohistochemistry and electron microscopy.
