Da Silva Aleksandro S, Costa Marcio M, Cargnelutti Juliana F, Lopes Sonia Terezinha Dos A, Monteiro Silvia G
Bolsista de Iniciação Científica da Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brasil.
Rev Bras Parasitol Vet. 2007 Jan-Mar;16(1):43-6.
The purpose of the present paper has been evaluating the biochemical changes in rabbits experimentally infected by Trypanosome evansi. Six male rabbits, separated in two groups, were used with the group A, the control group, being composed by non-infected animals and the group B composed by rodents infected with a T. evansi stump. The animals were maintained at room temperature and they have been analyzed during 120 days through 5 blood collections on days 1, 20, 40, 60 and 120. The biochemical changes observed in the infected rabbits were hyperproteinemia, hyperglobulinemia, increase on the urea levels, and significant decrease on ALT and albumin. The creatinine remained within the normality parameters. The rodents belonging to the group B have shown biochemical changes even after 80 days when the protozoon was not observed in the circulation anymore.
本文的目的是评估实验感染伊氏锥虫的家兔的生化变化。选用6只雄性家兔，分为两组，A组为对照组，由未感染动物组成，B组由感染伊氏锥虫残株的家兔组成。动物饲养在室温下，在120天内通过在第1、20、40、60和120天采集5次血液进行分析。在感染家兔中观察到的生化变化有高蛋白血症、高球蛋白血症、尿素水平升高以及谷丙转氨酶和白蛋白显著降低。肌酐仍在正常参数范围内。B组的家兔即使在80天后循环中未再观察到原虫时仍表现出生化变化。
