Ockene J K, Hymowitz N, Lagus J, Shaten B J
Department of Medicine, University of Massachusetts Medical School, Worcester 01655.
Prev Med. 1991 Sep;20(5):564-73. doi: 10.1016/0091-7435(91)90055-9.
The results of MRFIT smoking intervention program are presented for the 4,103 special intervention and 4,091 usual care men who reported smoking cigarettes at the first screening visit.
Among the special intervention men, the reported cessation rate increased from 43.1% at 12 months to 48.9% at 72 months. The reported cessation rate among the usual care men increased from 13.5% at 12 months to 28.8% at 72 months. Among smokers who reported cessation at 72 months, 51.3% of special intervention men and 22.7% of usual care men had quit smoking within the first year and remained abstinent thereafter. Average thiocyanate and expired-air carbon monoxide served as objective measures of smoking and were significantly lower among the special intervention men than among the usual care men over the entire follow-up period. The reported cessation rates at 72 months varied according to initial levels of smoking. Smokers reporting 1-19 cigarettes per day at entry were more likely to quit than heavier smokers. For each category of smoking at entry (1-19, 20-39, and 40 or more cigarettes per day) significantly more special intervention than usual care smokers reported cessation.
These results indicate that the MRFIT smoking intervention program was successful in promoting early cigarette smoking cessation and maintaining cessation over the entire trial for a large percentage of cigarette smokers.
本文呈现了多重危险因素干预试验（MRFIT）吸烟干预项目针对在首次筛查访视时报告吸烟的4103名特殊干预男性和4091名常规护理男性的结果。
在特殊干预男性中，报告的戒烟率从12个月时的43.1%升至72个月时的48.9%。常规护理男性的报告戒烟率从12个月时的13.5%升至72个月时的28.8%。在72个月时报告戒烟的吸烟者中，51.3%的特殊干预男性和22.7%的常规护理男性在第一年就戒烟并此后保持戒烟状态。平均硫氰酸盐和呼出气体一氧化碳作为吸烟的客观指标，在整个随访期间，特殊干预男性显著低于常规护理男性。72个月时报告的戒烟率根据初始吸烟水平而有所不同。初次筛查时报告每天吸1 - 19支烟的吸烟者比吸烟量更大者更有可能戒烟。对于每个初始吸烟类别（每天1 - 19支、20 - 39支以及40支或更多），报告戒烟的特殊干预吸烟者显著多于常规护理吸烟者。
这些结果表明，MRFIT吸烟干预项目成功地促进了大量吸烟者在整个试验期间早期戒烟并维持戒烟状态。
