Sadykov A S
Probl Tuberk. 1991(8):36-8.
The follow-up of 301 patients with fibrous-cavernous pulmonary tuberculosis has demonstrated that the disease outcome and treatment effectiveness depend on the nature of its course. A long-term specific therapy for 9-10 months brings about cessation of bacillary excretion in 50-60% of cases even in a progressive course of the disease and closure of destruction cavities occurred in 12.5% of cases with rapid progression and in 21.7% of cases with slow progression of the disease. Despite all measures taken, stabilization of the process fails in one-fourth of the patients with rapidly progressing fibrous-cavernous tuberculosis and in 9% of those with a slowly progressing course. In 90% of cases bacillary excretion in patients with stable fibrous-cavernous tuberculosis ceased in 3 months and in 100% after 6 months of treatment.
对301例纤维空洞型肺结核患者的随访表明,疾病转归和治疗效果取决于病程特点。即便疾病处于进展期,9至10个月的长期特异性治疗仍能使50%至60%的病例停止排菌,在疾病快速进展的病例中,12.5%的空洞得以闭合,疾病缓慢进展的病例中这一比例为21.7%。尽管采取了所有措施,快速进展的纤维空洞型肺结核患者中有四分之一、疾病缓慢进展的患者中有9%的病情未能得到稳定。在纤维空洞型肺结核病情稳定的患者中,90%的病例在治疗3个月后排菌停止,6个月后100%停止排菌。