Blakeslee J R, Olsen R G, McAllister E S, Fassbender J, Dennis R
Can J Microbiol. 1975 Dec;21(12):1940-6. doi: 10.1139/m75-281.
Five horses were experimentally exposed to equine herpesvirus 2 strain LK. Two young foals developed chronic pharyngitis (98 and 232 days, respectively). Growth characteristics, cytopathic effects (CPE), inclusion body formation, ether sensitivity, and immunofluorescent analysis indicated that the virus recovered from infected animals was a herpesvirus serologically identical with, or at least antigenically related to EHV-2 strain LK. No significant complement-fixing (CF) or virus-neutralizing (VN) antibody responses were observed in adult horses while both foals demonstrated a rise in CF antibody titer. One of the two foals demonstrated a rise in VN antibody only. The results suggest that EHV-2 virus induced chronic pharyngitis, primarily the result of lymphoid proliferation, with no overt clinical signs.
五匹马被实验性地暴露于马疱疹病毒2型LK毒株。两匹幼驹分别在98天和232天出现慢性咽炎。生长特性、细胞病变效应（CPE）、包涵体形成、乙醚敏感性和免疫荧光分析表明，从感染动物体内分离出的病毒是一种血清学上与马疱疹病毒2型LK毒株相同或至少抗原相关的疱疹病毒。成年马未观察到明显的补体结合（CF）或病毒中和（VN）抗体反应，而两匹幼驹的CF抗体滴度均升高。两匹幼驹中的一匹仅VN抗体滴度升高。结果表明，马疱疹病毒2型病毒诱发慢性咽炎，主要是淋巴组织增生的结果，无明显临床症状。
