Cole Tim J, Flegal Katherine M, Nicholls Dasha, Jackson Alan A
Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London WC1N 1EH.
BMJ. 2007 Jul 28;335(7612):194. doi: 10.1136/bmj.39238.399444.55. Epub 2007 Jun 25.
To determine cut offs to define thinness in children and adolescents, based on body mass index at age 18 years.
International survey of six large nationally representative cross sectional studies on growth.
Brazil, Great Britain, Hong Kong, the Netherlands, Singapore, and the United States.
97 876 males and 94 851 females from birth to 25 years.
Body mass index (BMI, weight/height(2)).
The World Health Organization defines grade 2 thinness in adults as BMI <17. This same cut off, applied to the six datasets at age 18 years, gave mean BMI close to a z score of -2 and 80% of the median. Thus it matches existing criteria for wasting in children based on weight for height. For each dataset, centile curves were drawn to pass through the cut off of BMI 17 at 18 years. The resulting curves were averaged to provide age and sex specific cut-off points from 2-18 years. Similar cut offs were derived based on BMI 16 and 18.5 at 18 years, together providing definitions of thinness grades 1, 2, and 3 in children and adolescents consistent with the WHO adult definitions.
The proposed cut-off points should help to provide internationally comparable prevalence rates of thinness in children and adolescents.
根据18岁时的体重指数确定儿童和青少年消瘦的界值。
对六项具有全国代表性的大型生长横断面研究进行国际调查。
巴西、英国、中国香港、荷兰、新加坡和美国。
97876名男性和94851名女性,年龄从出生至25岁。
体重指数(BMI,体重/身高²)。
世界卫生组织将成年人的2级消瘦定义为BMI<17。将这一相同的界值应用于18岁时的六个数据集,得出的平均BMI接近z评分-2以及中位数的80%。因此,它与基于身高体重的儿童消瘦现有标准相匹配。对于每个数据集,绘制百分位曲线使其在18岁时通过BMI 17的界值。将所得曲线进行平均,以提供2至18岁的年龄和性别特异性界值点。基于18岁时的BMI 16和18.5得出了类似的界值,共同给出了与世界卫生组织成人定义一致的儿童和青少年1级、2级和3级消瘦的定义。
所提出的界值点应有助于提供国际可比的儿童和青少年消瘦患病率。