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消除先天性梅毒:世界卫生组织拟议的消除先天性梅毒行动计划与现有国家孕产妇和先天性梅毒政策的比较

The elimination of congenital syphilis: a comparison of the proposed World Health Organization action plan for the elimination of congenital syphilis with existing national maternal and congenital syphilis policies.

作者信息

Hossain Mazeda, Broutet Nathalie, Hawkes Sarah

机构信息

Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.

出版信息

Sex Transm Dis. 2007 Jul;34(7 Suppl):S22-30. doi: 10.1097/01.olq.0000261049.84824.40.

Abstract

BACKGROUND AND OBJECTIVES

Building upon a critical assessment of national policies, programs, and treatment options, the World Health Organization (WHO) recently developed an action plan for the elimination of congenital syphilis (CS). The objective of the review was to identify areas of commonality or divergence between the national strategies and the WHO plan, thereby helping to target the development of national-level policies in light of the forthcoming recommendations of the proposed WHO action plan to eliminate CS.

STUDY DESIGN

The 4 strategic pillars of the proposed WHO action plan were used as a comparative framework to examine the policy, programmatic, and monitoring components of a sample of 14 existing national-level congenital or maternal control policies. The countries were chosen to represent a range of resource and prevalence levels.

RESULTS

The majority of countries do not meet every element proposed in the WHO action plan. Political commitment (pillar 1) across the 14 countries is varied. CS elimination goals were rare but all had universal screening. Linkages to appropriate case management services were identified in 11 countries, although a national governing body was not generally evident. Efforts to increase and improve access to care (pillar 2) were noted in 8 countries with recommendations to ensure all pregnant women were screened and treated. Low-resource settings have formed international partnerships. Guidelines for the diagnosis and treatment of pregnant women and partners (pillar 3) found in high-resource settings were lacking in low-resource and high CS prevalence countries. Surveillance programs were active in 10 countries while comprehensive details on monitoring and evaluation (pillar 4) components including proxy CS indicators were unavailable for nearly all.

CONCLUSIONS

The elimination of CS can be achieved through the implementation of a series of proven measures but requires technical support, funding, and a commitment among political forces, health officials, and the public to prevent and treat all CS cases and help countries reach their Millennium Development Goals. Stronger partnerships with clearly defined responsibilities should be developed among agencies responsible for national STI control, HIV/AIDS control, and Making Pregnancy Safer initiatives to ensure the universal coverage of CS control interventions.

摘要

背景与目标

在对国家政策、项目及治疗方案进行批判性评估的基础上,世界卫生组织(WHO)近期制定了一项消除先天性梅毒(CS)的行动计划。本综述的目的是确定国家战略与WHO计划之间的共性或差异领域,从而根据WHO拟议的消除CS行动计划的即将出台的建议,帮助确定国家级政策的制定方向。

研究设计

WHO拟议的行动计划的4个战略支柱被用作比较框架,以审查14项现有国家级先天性或孕产妇控制政策样本的政策、项目及监测组成部分。所选国家代表了不同的资源和流行率水平。

结果

大多数国家未达到WHO行动计划提出的各项要求。14个国家的政治承诺(支柱1)各不相同。消除CS的目标很少见,但都进行了普遍筛查。11个国家确定了与适当病例管理服务的联系,尽管通常没有国家管理机构。8个国家注意到为增加和改善获得护理的机会所做的努力(支柱2),并建议确保对所有孕妇进行筛查和治疗。资源匮乏地区建立了国际伙伴关系。资源匮乏和CS高流行率国家缺乏资源丰富地区所采用的孕妇及其性伴侣诊断和治疗指南(支柱3)。10个国家的监测项目很活跃,但几乎所有国家都没有关于监测和评估(支柱4)组成部分(包括代理CS指标)的全面详细信息。

结论

通过实施一系列行之有效的措施可以实现消除CS的目标,但需要技术支持、资金以及政治力量、卫生官员和公众的承诺,以预防和治疗所有CS病例,并帮助各国实现其千年发展目标。负责国家性传播感染控制、艾滋病毒/艾滋病控制及“使妊娠更安全”倡议的机构之间应建立责任明确的更强有力的伙伴关系,以确保CS控制干预措施的普遍覆盖。

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