Smith Torben Aagaard, Fabricius Martin Ejler
Glostrup Hospital, Klinisk Neurofysiologisk Afdeling, Glostrup.
Ugeskr Laeger. 2007 Jun 4;169(23):2216-9.
Critically-ill patients in intensive care units often suffer from weakness of the arms and legs and have difficulty in weaning from the ventilator. If this cannot be explained by the illness itself, it may be due to a critical illness polyneuropathy (CIP) or a critical illness myopathy (CIM) or both. It is difficult to determine the cause of the weakness by conventional methods in an intensive care unit. The objective was to describe the diagnostic yield with electrodiagnostic testing and describe the various patterns and prognosis in these patients.
55 consecutive patients with a critical illness associated with unexplained weakness of limbs and often respiratory muscles were studied to estimate motor and sensory nerve conduction, electromyography, direct muscle stimulation, and repetitive nerve stimulation.
18 patients had CIM, 16 had CIP and in 9 a combination of CIM and CIP was found. Direct muscle stimulation was more sensitive to show myogenic affection than needle EMG in this patient group.
Electrophysiologic tests are valuable in identifying the specific cause of prolonged weakness in critically-ill patients in intensive care units.
重症监护病房中的重症患者常出现四肢无力,且难以脱机。如果这不能用疾病本身来解释,可能是由于重症疾病性多发性神经病(CIP)或重症疾病性肌病(CIM)或两者兼有。在重症监护病房中,用传统方法很难确定无力的原因。目的是描述电诊断测试的诊断率,并描述这些患者的各种模式和预后。
对55例患有与不明原因肢体无力(常累及呼吸肌)相关的重症疾病的患者进行研究,以评估运动和感觉神经传导、肌电图、直接肌肉刺激和重复神经刺激。
18例患者患有CIM,16例患有CIP,9例患者同时存在CIM和CIP。在该患者组中,直接肌肉刺激比针极肌电图对显示肌源性病变更敏感。
电生理测试对于确定重症监护病房中重症患者长期无力的具体原因很有价值。