Maramattom Bobby Varkey, Wijdicks Eelco F M
Department of Neurology, Lourdes Hospital, Kochi, Kerala, India.
Crit Care Med. 2006 Nov;34(11):2835-41. doi: 10.1097/01.CCM.0000239436.63452.81.
Patients in the intensive care unit develop generalized weakness due to a number of factors. Neuromuscular weakness is a common cause of failure to wean from the ventilator and decreased limb movements. A rational approach to evaluation of weakness will help to identify most of the common causes of neuromuscular weakness in the intensive care unit.
This review provides an analysis of neuromuscular weakness and a practical algorithm to assist in diagnostic evaluation.
The most common acquired causes of weakness in the critically ill patient in the intensive care unit are critical illness polyneuropathy and critical illness myopathy. In the intensive care unit setting, electrophysiological studies, biopsies, and imaging studies are often necessary to complement the clinical impression.
重症监护病房的患者由于多种因素会出现全身无力。神经肌肉无力是导致脱机失败和肢体活动减少的常见原因。对无力进行合理评估有助于识别重症监护病房中神经肌肉无力的大多数常见病因。
本综述对神经肌肉无力进行分析,并提供一种实用的算法以辅助诊断评估。
重症监护病房中危重症患者最常见的后天性无力病因是重症疾病性多发性神经病和重症疾病性肌病。在重症监护病房环境中,电生理检查、活检和影像学检查通常是补充临床判断所必需的。