Nyrop K A, Palsson O S, Levy R L, Von Korff M, Feld A D, Turner M J, Whitehead W E
Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina, Chapel Hill, NC 27599-7080, USA.
Aliment Pharmacol Ther. 2007 Jul 15;26(2):237-48. doi: 10.1111/j.1365-2036.2007.03370.x.
To provide estimates of actual costs to deliver health care to patients with functional bowel disorders, and to assess the cost impact of symptom severity, recency of onset, and satisfaction with treatment.
We enrolled 558 irritable bowel (IBS), 203 constipation, 243 diarrhoea and 348 abdominal pain patients from primary care and gastroenterology clinics at a health maintenance organization within weeks of a visit. Costs were extracted from administrative claims. Symptom severity, satisfaction with treatment and out-of-pocket expenses were assessed by questionnaires.
Average age was 52 years, 27% were males, and 59% participated. Eighty percent were seen in primary care clinics. Mean annual direct health care costs were $5049 for IBS, $6140 for diarrhoea, $7522 for constipation and $7646 for abdominal pain. Annual out-of-pocket expenses averaged $406 for treatment of IBS symptoms, $294 for diarrhoea, $390 for constipation and $304 for abdominal pain. Lower gastrointestinal costs comprised 9% of total costs for IBS, 9% for diarrhoea, 6.5% for constipation and 9% for abdominal pain. In-patient care accounted for 17.5% of total costs (15.2% IBS).
Costs were affected by disease severity (increased), recent exacerbation of bowel symptoms (increased), and whether the patient was consulting for the first time (decreased).
估算为功能性肠病患者提供医疗服务的实际成本,并评估症状严重程度、发病近期情况及治疗满意度对成本的影响。
我们在一家健康维护组织的初级保健和胃肠病诊所,于患者就诊数周内招募了558例肠易激综合征(IBS)患者、203例便秘患者、243例腹泻患者和348例腹痛患者。成本数据从行政索赔中提取。通过问卷调查评估症状严重程度、治疗满意度和自付费用。
平均年龄为52岁,27%为男性,59%参与调查。80%的患者在初级保健诊所就诊。IBS患者的年均直接医疗成本为5049美元,腹泻患者为6140美元,便秘患者为7522美元,腹痛患者为7646美元。IBS症状治疗的年均自付费用平均为406美元,腹泻为294美元,便秘为390美元,腹痛为304美元。下消化道成本占IBS总成本的9%,腹泻为9%,便秘为6.5%,腹痛为9%。住院护理占总成本的17.5%(IBS为15.2%)。
成本受疾病严重程度(增加)、肠道症状近期加重(增加)以及患者是否首次咨询(降低)的影响。