Wang Shih-Ho, Chen Chao-Long, Concejero Allan, Wang Chih-Chi, Lin Chih-Che, Liu Yueh-Wei, Yang Chin-Hsiang, Yong Chee-Chien, Lin Tsan-Shiun, Chiang Yuan-Cheng, Jawan Bruno, Huang Tung-Liang, Cheng Yu-Fan, Eng Hock-Liew
Liver Transplantation Program, Department of Surgery, Chang Gung Memorial Hospital. 123, Dapi Rd., Niaosong Township, Kaohsiung County 833, Taiwan, ROC.
Chang Gung Med J. 2007 Mar-Apr;30(2):103-8.
Biliary atresia is the most common cause of chronic cholestasis in infants and children. The incidence is estimated at 3.7:10,000 among Taiwanese infants. Kasai hepatoportoenterostomy helps children survive beyond infancy. Liver transplantation is indicated when the Kasai procedure fails to work or when patients develop progressive deterioration of liver function despite an initially successful Kasai operation. Living donor liver transplantation was developed to alleviate organ shortage from deceased donors. It has decreased the waiting time for transplantation and, therefore, improves patient survival. One hundred living donor liver transplantations have been performed for biliary atresia at Chang Gung Memorial Hospital-Kaohsiung Medical Center with both 98% 1-year and 5-year actual recipient survival.
胆道闭锁是婴幼儿慢性胆汁淤积最常见的病因。据估计，台湾地区婴儿的发病率为3.7∶10000。葛西肝门肠吻合术可帮助患儿存活至婴儿期之后。当葛西手术失败，或尽管最初葛西手术成功，但患者出现肝功能进行性恶化时，则需进行肝移植。活体供肝肝移植的开展是为了缓解尸体供肝的短缺。它缩短了移植等待时间，从而提高了患者生存率。长庚纪念医院高雄医学中心已对胆道闭锁患者实施了100例活体供肝肝移植，受者1年和5年实际生存率均为98%。
