Glaser Dee Anna, Hebert Adelaide A, Pariser David M, Solish Nowell
Department of Dermatology, Saint Louis University, Missouri, USA.
Cutis. 2007 May;79(5 Suppl):5-17.
Focal hyperhidrosis (HH) can cause debilitating reductions in the physical and emotional quality of life (QOL) of patients, which can result in numerous restrictions of a patient's personal and professional lifestyle and activities. A variety of treatment options are available for primary focal HH, including topical and oral agents, tap water iontophoresis (TWI), botulinum toxin type A (BTX-A), and surgery. Studies evaluating BTX-A (Botox) treatment for palmar, plantar, and facial HH reveal that BTX-A provides effective treatment of primary focal HH, with a reasonable duration of effect, and has a good safety profile. Physicians should understand the impact of focal HH and the need to stay abreast of the available treatment options to provide the best care for patients.
局限性多汗症（HH）会导致患者身体和情绪生活质量（QOL）严重下降，进而造成患者个人及职业生活方式与活动的诸多限制。原发性局限性HH有多种治疗选择，包括局部和口服药物、自来水离子导入法（TWI）、A型肉毒杆菌毒素（BTX-A）及手术。评估BTX-A（保妥适）治疗手掌、足底和面部HH的研究表明，BTX-A能有效治疗原发性局限性HH，疗效持续时间合理，且安全性良好。医生应了解局限性HH的影响，并及时掌握可用的治疗选择，以便为患者提供最佳治疗。
