Tanaka F, Emi K, Danjo S
Eye Clinic, Osaka Rosai Hospital, Sakai, Japan.
Nippon Ganka Gakkai Zasshi. 1991 Nov;95(11):1129-34.
The aqueous protein level (APL) in eyes of rhegmatogenous retinal detachment (RRD) combined with or without choroidal detachment (CD) was investigated using a laser flare-cell meter. The APL in eyes of RRD with CD was 70 times higher than in eyes of simple RRD. The APL increased suddenly with the appearance of CD and decreased rapidly in accordance with the disappearance of CD. The longer the CD continued, the higher the APL remained preoperatively as well as postoperatively. The APL in eyes of RRD with CD was still twice as high as in eyes of simple RRD 6 months after successful retinal reattachment. This marked and prolonged intraocular inflammation in eyes of RRD with CD might result in a poorer visual outcome. The extremely high APL might be caused by reflux of suprachoroidal protein through the uveoscleral route and/or venous protein through the trabecular meshwork due to ocular hypotony and possibly by diffusion of protein via posterior chamber and vitreous cavity due to the breakdown of the blood-ocular barrier.
使用激光散射细胞仪研究了孔源性视网膜脱离(RRD)合并或不合并脉络膜脱离(CD)患者眼内的房水蛋白水平(APL)。合并CD的RRD患者眼内的APL比单纯RRD患者眼内的APL高70倍。APL随着CD的出现而突然升高,并随着CD的消失而迅速下降。CD持续的时间越长,术前和术后的APL就越高。视网膜复位成功6个月后,合并CD的RRD患者眼内的APL仍比单纯RRD患者眼内的APL高两倍。合并CD的RRD患者眼内这种明显且持续时间长的眼内炎症可能导致较差的视觉预后。极高的APL可能是由于眼压降低,脉络膜上腔蛋白通过葡萄膜巩膜途径反流和/或静脉蛋白通过小梁网反流所致,也可能是由于血眼屏障破坏,蛋白通过后房和玻璃体腔扩散所致。