Betrus P A, Elmore S K
Department of Psychosocial Nursing, University of Washington, Seattle 98185.
Arch Psychiatr Nurs. 1991 Dec;5(6):357-64. doi: 10.1016/0883-9417(91)90037-6.
This article is the first of a two-part series on Seasonal Affective Disorder (SAD). Mental health and nursing researchers are beginning to investigate the implications of seasons on mood and mood states. Delineation of SAD and its treatment by phototherapy is an example. This article reviews the pertinent research regarding the hypothesized neural mechanisms of SAD. Three competing hypothesis are contrasted and compared: the melatonin hypothesis, the phase delay hypothesis, and the photon counting hypothesis. Although no one theory is universally accepted, current data supports the phase delay hypothesis and suggests that morning phototherapy is the most effective treatment.
本文是关于季节性情感障碍（SAD）的系列文章的第一篇，共两部分。心理健康和护理研究人员开始研究季节对情绪和情绪状态的影响。对季节性情感障碍及其光疗法治疗的描述就是一个例子。本文回顾了关于季节性情感障碍假定神经机制的相关研究。对比并比较了三种相互竞争的假说：褪黑素假说、相位延迟假说和光子计数假说。虽然没有一种理论被普遍接受，但目前的数据支持相位延迟假说，并表明早晨光疗法是最有效的治疗方法。
