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[心血管手术中自体输血程序的优势与局限性。基于524例患者的研究]

[Advantages and limits of programmed autologous transfusion in cardiovascular surgery. Apropos of 524 patients].

作者信息

Massonnet-Castel S, Fabiani J N, Jebara V, Rubino P, Pelissier E, Deloche A, Terrier E, Carpentier A

机构信息

Centre de transfusion sanguine, hôpital Broussais, Paris.

出版信息

Arch Mal Coeur Vaiss. 1991 Oct;84(10):1447-52.

PMID:1759897
Abstract

Between October 1987 and July 1989, 544 patients, candidates for cardiovascular surgery, were included in a trial of programmed autologous autotransfusion. Five hundred and twenty four patients underwent one or several (maximum 4) blood donation sessions in the 3 weeks before surgery with no complications. Overall, 57% of patients benefited from homologous blood transfusion, thereby avoiding all risk of contamination. It was in the group of patients able to undergo 3 or 4 preoperative blood donations that we observed the smallest number of homologous transfusions (30%). Programmed autologous transfusion would seem to be a very useful technique for cardiac surgery, allowing a reduction in health care costs without additional patient risk. In order to improve on this method, it may be useful to associate a peroperative technique of blood recuperation in patients in whom the transfusion needs are likely to exceed the possibilities of preoperative blood donation alone.

摘要

1987年10月至1989年7月期间,544名心血管手术候选患者被纳入自体预存输血试验。524名患者在手术前3周进行了一次或几次(最多4次)献血,无并发症。总体而言,57%的患者受益于异体输血,从而避免了所有感染风险。正是在能够进行3次或4次术前献血的患者组中,我们观察到异体输血的数量最少(30%)。自体预存输血似乎是心脏手术中一种非常有用的技术,可在不增加患者风险的情况下降低医疗成本。为了改进这种方法,对于输血需求可能超过单纯术前献血可能性的患者,联合术中血液回收技术可能会有所帮助。

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