Adepoju F G, Olawumi H O, Adekoya B J
Department of Ophthalmology, College of Medicine, University of Ilorin.
Niger Postgrad Med J. 2007 Jun;14(2):163-5.
HIV is assuming an alarming pandemic worldwide and presently in Nigeria it is a source of concern to all and sundry.
To review the demography of cases positive for HIV in the eye clinic over a 5-year period and to identify ocular diseases that have high predictive value for HIV.
A retrospective study of all the patients that were screened for HIV in the eye clinic over a 5-year period was done. Screening was by ELISA method with confirmation by Western blot test.
A total of 60 patients were screened and 26 (43.3%) of them were HIV positive. The male to female ratio of HIV positive patients was 1:1. All the seropositive patients were between the ages of 20-49 years and about a third were students from the higher institutions. Half of the patients were single. Diagnoses with high predictive values were Herpes Zoster Ophthalmicus (62%), Steven Johnson syndrome (50%), HIV retinopathy (75%), Bilateral Unresolving Toxoplasmosis (42%). The common presentations however are Herpes Zoster Ophthalmicus (HZO) and unresolving bilateral Uveitis.
HIV and ocular involvement is increasing in Ilorin. The high-risk groups among patients presenting to the hospital are students of higher institutions and Soldiers. Diseases of high predictive indices are Herpes zoster Ophthalmicus, Steven Johnson's syndrome, HIV retinopathy.
艾滋病病毒在全球范围内正呈现出令人担忧的流行态势，目前在尼日利亚，它是所有人都关心的问题。
回顾眼科门诊5年内艾滋病毒检测呈阳性病例的人口统计学特征，并确定对艾滋病毒具有高预测价值的眼部疾病。
对眼科门诊5年内所有接受艾滋病毒筛查的患者进行回顾性研究。筛查采用酶联免疫吸附测定法，并通过蛋白质印迹试验进行确认。
共筛查了60例患者，其中26例（43.3%）艾滋病毒检测呈阳性。艾滋病毒阳性患者的男女比例为1:1。所有血清学阳性患者年龄在20至49岁之间，约三分之一是高等院校的学生。一半患者为单身。具有高预测价值的诊断包括眼部带状疱疹（62%）、史蒂文斯-约翰逊综合征（50%）、艾滋病毒视网膜病变（75%）、双侧未缓解的弓形虫病（42%）。然而，常见的表现是眼部带状疱疹（HZO）和未缓解的双侧葡萄膜炎。
伊洛林地区艾滋病毒与眼部受累情况正在增加。到医院就诊的患者中的高危人群是高等院校学生和军人。具有高预测指标的疾病是眼部带状疱疹、史蒂文斯-约翰逊综合征、艾滋病毒视网膜病变。
