Martin Timothy J, Conley Stephen F
Department of Otolaryngology, Division of Pediatric Otolaryngology, Children's Hospital of Wisconsin, Medical College of WI, Milwaukee, WI 53226, USA.
Otolaryngol Head Neck Surg. 2007 Jul;137(1):54-8. doi: 10.1016/j.otohns.2007.01.034.
To investigate the efficacy and quality of life impact of intra-oral surgery for sialorrhea and to provide long-term outcome measures.
A retrospective review and telephone survey of patients seen in a multi-disciplinary saliva control clinic who underwent surgery between 1999 and 2003.
Sixteen of 31 patients underwent 4-duct ligation, 12 patients underwent submandibular gland duct ligation, and three patients underwent a 3-duct ligation procedure. The mean presurgical drooling score (maximum 10) was 9.5, 8.8, and 9, respectively. Recurrence was seen in 68% of patients at a mean of four months. Additional surgery was required in five patients. Phone survey was accomplished in 10 patients. Two of 10 caregivers reported sustained improvement of sialorrhea at two and three years.
Intra-oral surgery provides minimal long-term control of sialorrhea. Additional medical and surgical therapy was needed in a significant portion of patients in this long-term review.
研究口腔内手术治疗流涎症的疗效及对生活质量的影响，并提供长期疗效指标。
对1999年至2003年间在多学科唾液控制诊所接受手术的患者进行回顾性研究及电话调查。
31例患者中，16例行四导管结扎术，12例行下颌下腺导管结扎术，3例行三导管结扎术。术前平均流口水评分（满分10分）分别为9.5分、8.8分和9分。68%的患者在平均四个月时出现复发。5例患者需要再次手术。对10例患者进行了电话调查。10名护理人员中有2名报告说，在术后两年和三年时流涎症持续改善。
口腔内手术对流涎症的长期控制效果甚微。在这项长期研究中，相当一部分患者需要额外的药物和手术治疗。
