Brodtmann Amy, Puce Aina, Darby David, Donnan Geoffrey
Stroke. 2007 Aug;38(8):2360-3. doi: 10.1161/STROKEAHA.106.480574. Epub 2007 Jun 28.
Diaschisis may play a critical role in motor recovery, but in other cortical networks its role is unclear. Some visual system regions, such as the fusiform gyri, depend on intact striate regulation for their function. We evaluated visual cortical diaschisis by serial functional magnetic resonance imaging.
Using a high-level visual activation task, we studied patients with visual system stroke by functional magnetic resonance imaging within 10 days and at 6 months. Their activation data were compared with those of age-appropriate healthy control subjects.
Three patients were studied. In the short term, patients displayed absent or significantly reduced activation in ventral extrastriate sites. All displayed a restitution of activation to these sites at 6 months.
Functional magnetic resonance imaging revealed evidence of ipsilesional cortical diaschisis within ventral extrastriate sites. Diaschisis may play an under-recognized role in visual recovery after stroke.
失联络现象可能在运动恢复中起关键作用，但在其他皮质网络中其作用尚不清楚。一些视觉系统区域，如梭状回，其功能依赖于完整的纹状皮质调节。我们通过系列功能磁共振成像评估视觉皮质失联络现象。
采用高级视觉激活任务，我们在10天内及6个月时通过功能磁共振成像研究视觉系统卒中患者。将他们的激活数据与年龄匹配的健康对照者的数据进行比较。
研究了3例患者。短期内，患者在腹侧纹外区部位的激活缺失或显著降低。所有患者在6个月时这些部位的激活均恢复。
功能磁共振成像显示腹侧纹外区部位存在同侧皮质失联络现象的证据。失联络现象可能在卒中后视觉恢复中起未被充分认识的作用。
