Schlaggar Bradley L, McCandliss Bruce D
Department of Neurology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Annu Rev Neurosci. 2007;30:475-503. doi: 10.1146/annurev.neuro.28.061604.135645.
Functional and structural neuroimaging studies of adult readers have provided a deeper understanding of the neural basis of reading, yet such findings also elicit new questions about how developing neural systems come to support this learned ability. A developmental cognitive neuroscience approach provides insights into how skilled reading emerges in the developing brain, yet also raises new methodological challenges. This review focuses on functional changes that occur during reading acquisition in cortical regions associated with both the perception of visual words and spoken language, and it examines how such functional changes differ within developmental reading disabilities. We integrate these findings within an interactive specialization framework of functional development and propose that such a framework may provide insights into how individual differences at several levels of observation (genetics, white matter tract structure, functional organization of language, cultural organization of writing systems) impact the emergence of neural systems involved in reading ability and disability.
针对成年阅读者的功能和结构神经影像学研究,让我们对阅读的神经基础有了更深入的理解,但这些研究结果也引发了新的问题,即发育中的神经系统如何支持这种后天习得的能力。发展认知神经科学的方法有助于我们了解在发育中的大脑中,熟练阅读能力是如何出现的,但同时也带来了新的方法学挑战。本综述聚焦于与视觉单词感知和口语相关的皮层区域在阅读习得过程中发生的功能变化,并探讨这些功能变化在发育性阅读障碍中有何不同。我们将这些研究结果整合到一个功能发展的交互式专业化框架中,并提出这样一个框架或许能为我们提供见解,以了解在多个观察层面(遗传学、白质束结构、语言的功能组织、书写系统的文化组织)上的个体差异如何影响参与阅读能力和阅读障碍的神经系统的出现。