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[幽门螺杆菌感染时粪便中幽门螺杆菌唾液酸结合粘附素抗原的研究]

[The study of the presence of HpSA antigens in the faeces in Helicobacter pylori infection].

作者信息

Leszczyńska Katarzyna, Jakoniuk Piotr, Namiot Zbigniew

机构信息

Zakład Diagnostyki Mikrobiologicznej Akademii Medycznej w Białymstoku.

出版信息

Med Dosw Mikrobiol. 2007;59(1):51-8.

Abstract

A total of 154 adult patients with dyspeptic symptoms were studied. In case of 115 (74,68%) persons Helicobacter pylori infection was detected, taking into consideration positive results in a rapid urease test and histological examination and presence of antibodies in the serum. In 69,6% predominated high (> 72 IU/ml) level specific anty-H. pylori antibodies. In stool, antigen H. pylori was detected in 100 (64,9%) samples. In 137 cases were obtained results, this same like results of three early tests. Senitivity and specificity of HpSA test were 86,21% and 98,18%, respectively. It was significant (13,91%) percenage of false negative results.

摘要

共对154名有消化不良症状的成年患者进行了研究。在115人(74.68%)中检测到幽门螺杆菌感染,这是综合考虑快速尿素酶试验、组织学检查的阳性结果以及血清中抗体的存在得出的。在69.6%的患者中,高水平(>72 IU/ml)的特异性抗幽门螺杆菌抗体占主导。在100份(64.9%)粪便样本中检测到幽门螺杆菌抗原。137例获得了检测结果,与三项早期检测结果相同。HpSA检测的敏感性和特异性分别为86.21%和98.18%。假阴性结果的比例为13.91%,具有显著性。

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