Povlsen Johan V, Ivarsen Per
Department of Renal Medicine C, Aarhus University Hospital, Skejby, Aarhus, Denmark.
Adv Chronic Kidney Dis. 2007 Jul;14(3):279-83. doi: 10.1053/j.ackd.2007.03.008.
Elderly patients are the largest and fastest growing group of patients with chronic kidney disease maintained on dialysis in the world. Because of advanced age and a heavy burden of comorbidities, the elderly are usually not candidates for kidney transplantation and are less likely to be offered peritoneal dialysis (PD). There is, however, growing evidence that the use of community nurses to assist with PD and the introduction of programs for assisted peritoneal dialysis (aPD) targeting these frail, elderly patients may enable more elderly patients to have their PD treatment at home. Suitable candidates for aPD are incident end-stage kidney disease patients preferring PD but unable to perform their own treatment because of comorbidities, physical disabilities, or psychosocial problems; prevalent, previous autonomous PD patients who have lost their independence because of advanced age or an increased burden of comorbidities; or prevalent hemodialysis (HD) patients switched from HD to aPD because of their own preference, failure of vascular access for HD, or an inability to tolerate HD. We believe that aPD in the future will prove to be a safe and feasible complementary alternative to in-center HD for the growing group of frail, elderly patients with end-stage kidney disease.
老年患者是全球接受透析治疗的慢性肾脏病患者中规模最大且增长最快的群体。由于年龄较大且合并症负担沉重,老年人通常不适合进行肾移植,接受腹膜透析(PD)的可能性也较小。然而,越来越多的证据表明,利用社区护士协助进行PD以及针对这些体弱老年患者引入辅助腹膜透析(aPD)项目,可能会使更多老年患者能够在家中接受PD治疗。aPD的合适人选包括:新发终末期肾病患者,他们倾向于选择PD,但由于合并症、身体残疾或心理社会问题而无法自行进行治疗;既往自主进行PD的患者,由于年龄增长或合并症负担加重而失去了独立性;或者是由于自身偏好、血液透析(HD)血管通路失败或无法耐受HD而从HD转为aPD的长期HD患者。我们相信,对于越来越多患有终末期肾病的体弱老年患者来说,未来aPD将被证明是一种安全可行的、可替代中心HD的补充选择。