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过去十年间辅助性腹膜透析的趋势:一项来自法国腹膜透析登记处的队列研究。

Trends in assisted peritoneal dialysis over the last decade: a cohort study from the French Peritoneal Dialysis Registry.

作者信息

Boyer Annabel, Lanot Antoine, Lambie Mark, Guillouet Sonia, Lobbedez Thierry, Béchade Clémence

机构信息

Centre Universitaire des Maladies Rénales, CHU de Caen, 14 033 Caen Cedex 9, France.

U1086, INSERM-ANTICIPE-Centre, Régional de Lutte contre, le Cancer, François Baclesse, Caen, France.

出版信息

Clin Kidney J. 2020 May 17;13(6):1003-1011. doi: 10.1093/ckj/sfaa051. eCollection 2020 Dec.

Abstract

BACKGROUND

There is limited information available on the use of assisted peritoneal dialysis (PD) over time and the impact of economic incentives on its utilization. The aim of this study was to describe the trends in assisted PD utilization and the type of assistance provided. We wanted to estimate if an economic incentive implemented in 2011 in France was associated with an increase in the utilization of nurse-assisted PD.

METHODS

This retrospective, multicentre study, based on data from the French Language Peritoneal Dialysis Registry, analysed 11 987 patients who initiated PD in France between 1 January 2006 and 31 December 2015. Adjusted Cox regression with robust variance was used to examine the initiation of assisted PD, both nurse-assisted and family-assisted, accounting for the nonlinear impact of the PD starting time.

RESULTS

There were 6149 (51%) incident patients on assisted PD, 5052 (82%) on nurse-assisted PD and 1097 (18%) on family-assisted PD over the study period. In the adjusted analysis, calendar time was associated with the assisted PD rate: it declined from 2008 until 2013 before flattening out and then it increased after 2014. Nurse-assisted PD utilization increased significantly after 2012, whereas family-assisted PD utilization decreased linearly over time (prevalence ratio = 0.94, 95% confidence interval 0.92-0.97).

CONCLUSIONS

The assisted PD rate decreased until 2013, mainly because of a decline in family-assisted PD. The uptake in nurse-assisted PD observed from 2013 reflects the effect of an economic incentive adopted in late 2011 to increase PD utilization.

摘要

背景

关于长期使用辅助性腹膜透析(PD)以及经济激励措施对其使用的影响,现有信息有限。本研究的目的是描述辅助性PD使用情况的趋势以及所提供的辅助类型。我们想评估2011年在法国实施的一项经济激励措施是否与护士辅助PD使用的增加有关。

方法

这项基于法语腹膜透析登记处数据的回顾性多中心研究,分析了2006年1月1日至2015年12月31日期间在法国开始进行PD的11987例患者。采用具有稳健方差的校正Cox回归分析来研究护士辅助和家庭辅助的辅助性PD的起始情况,同时考虑PD开始时间的非线性影响。

结果

在研究期间,有6149例(51%)新发病例接受辅助性PD,其中5052例(82%)接受护士辅助PD,1097例(18%)接受家庭辅助PD。在校正分析中,日历时间与辅助性PD率相关:从2008年到2013年呈下降趋势,之后趋于平稳,然后在2014年后有所上升。2012年后护士辅助PD的使用显著增加,而家庭辅助PD的使用随时间呈线性下降(患病率比 = 0.94,95%置信区间0.92 - 0.97)。

结论

辅助性PD率在2013年前下降,主要是由于家庭辅助PD的减少。2013年观察到的护士辅助PD的使用增加反映了2011年末为提高PD使用率而采取的经济激励措施的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0391/7769513/15db0d7b3807/sfaa051f1.jpg

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