Yin Zheng Qin, Wang Hui, Yu Tao, Ren Qian, Chen Li
Southwest Eye Hospital/Southwest Hospital, Chongqing, China.
J AAPOS. 2007 Dec;11(6):571-6. doi: 10.1016/j.jaapos.2007.04.014. Epub 2007 Jul 2.
To assess the efficacy of laser in situ keratomileusis (LASIK) in facilitating amblyopia management of children from 6 to 14 years old, with high hyperopic and myopic anisometropia.
Between 2000 and 2005, 42 children with high hyperopic anisometropic amblyopia and 32 children with high myopic anisometropic amblyopia underwent LASIK to reduce their anisometropia. LASIK was performed under topical or general anesthesia. Pre- and postoperative best-corrected visual acuity, cycloplegic refraction, and binocular vision were recorded. Follow-up ranged from 6 months to 3 years, the averages of which were 17.45 months in the hyperopic group and 18.31 months in myopic group.
Hyperopic anisometropia correction ranged from +3.50 D to +7.75 D, and the mean postoperative anisometropia was +0.56 +/- 0.75 D at 3 years. Myopic anisometropia correction ranged from -15.75 to -5.00 D and the mean postoperative anisometropia at 3 years was -2.20 +/- 1.05 D. The best-corrected visual acuity for distance and reading in the myopic group improved from 0.4 +/- 0.25 and 0.58 +/- 0.27, respectively, before surgery to 0.59 +/- 0.28 and 0.96 +/- 0.35, respectively, 3 years after surgery. In the hyperopic group, best-corrected visual acuity for distance and reading improved from 0.23 +/- 0.21 and 0.34 +/- 0.32, respectively, before surgery to 0.53 +/- 0.31 and 0.80 +/- 0.33, respectively, 3 years after surgery. The proportion of patients who had stereopsis increased from 19.1% preoperatively to 46.7% postoperatively in the hyperopic group and from 19% to 89% in the myopic group.
LASIK reduced high hyperopic and myopic anisometropia in children, thus facilitating amblyopia management and improving their visual acuity and stereopsis.
评估准分子原位角膜磨镶术（LASIK）对6至14岁患有高度远视和近视性屈光参差的儿童弱视治疗的疗效。
2000年至2005年间，42例患有高度远视性屈光参差性弱视的儿童和32例患有高度近视性屈光参差性弱视的儿童接受了LASIK手术以减少其屈光参差。LASIK手术在表面麻醉或全身麻醉下进行。记录术前和术后的最佳矫正视力、睫状肌麻痹验光结果和双眼视功能。随访时间为6个月至3年，远视组平均随访时间为17.45个月，近视组为18.31个月。
远视性屈光参差的矫正范围为+3.50 D至+7.75 D，术后3年平均屈光参差为+0.56±0.75 D。近视性屈光参差的矫正范围为-15.75至-5.00 D，术后3年平均屈光参差为-2.20±1.05 D。近视组术前远距离和阅读的最佳矫正视力分别为0.4±0.25和0.58±0.27，术后3年分别提高到0.59±0.28和0.96±0.35。远视组术前远距离和阅读的最佳矫正视力分别为0.23±0.21和0.34±0.32，术后3年分别提高到0.53±0.31和0.80±0.33。远视组具有立体视的患者比例从术前的19.1%增加到术后的46.7%，近视组从19%增加到89%。
LASIK降低了儿童高度远视和近视性屈光参差程度，从而有助于弱视治疗并提高其视力和立体视。
