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Biophysics of Parkinson's disease: structure and aggregation of alpha-synuclein.
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Accelerated formation of alpha-synuclein oligomers by concerted action of the 20S proteasome and familial Parkinson mutations.
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The good and bad of therapeutic strategies that directly target α-synuclein.
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Α-synuclein misfolding and Parkinson's disease.
Biochim Biophys Acta. 2012 Feb;1822(2):261-85. doi: 10.1016/j.bbadis.2011.10.002. Epub 2011 Oct 12.
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Pathogenic Impact of α-Synuclein Phosphorylation and Its Kinases in α-Synucleinopathies.
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Gene-Based Therapeutics for Parkinson's Disease.
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Brain regions susceptible to alpha-synuclein spreading.
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