Nakakura Eric K, Venook Alan P, Bergsland Emily K
Department of Surgery, Division of Surgical Oncology, University of California, UCSF Comprehensive Cancer Center, 1600 Divisadero Street, A-724, San Francisco, CA 94143-1932, USA.
Surg Oncol Clin N Am. 2007 Jul;16(3):639-51, x. doi: 10.1016/j.soc.2007.04.019.
A multidisciplinary team is essential for the optimal management of patients with metastatic neuroendocrine tumors. In this article, the systemic and regional nonsurgical therapeutic options for metastatic neuroendocrine cancers are discussed. In particular, the roles of biotherapy, chemotherapy, and hepatic artery embolization/chemoembolization are reviewed. A proposed treatment algorithm is provided with the aim of providing clinicians with a useful framework for managing these challenging patients. Finally, the rationale for promising investigational therapies is described.
多学科团队对于转移性神经内分泌肿瘤患者的最佳管理至关重要。本文讨论了转移性神经内分泌癌的全身和局部非手术治疗选择。特别回顾了生物疗法、化疗以及肝动脉栓塞/化疗栓塞的作用。提供了一种建议的治疗算法，旨在为临床医生管理这些具有挑战性的患者提供一个有用的框架。最后，描述了有前景的研究性治疗的基本原理。
