Dähnert I, Riede F T, Razek V, Weidenbach M, Rastan A, Walther T, Kostelka M
Dept. Pediatric Cardiology, Herzzentrum Leipzig GmbH, Universität Leipzig, Strümpellstr. 39, 04289 Leipzig, Germany.
Clin Res Cardiol. 2007 Oct;96(10):719-22. doi: 10.1007/s00392-007-0545-5. Epub 2007 Jul 11.
Shunts placed between the right ventricle and the pulmonary arteries, called Sano shunts, recently modified Norwood surgery for hypoplastic left heart syndrome. Patients with Sano shunts tend to be more stable thus reducing the interstage mortality of this still challenging complex cardiac anomaly. However, Sano shunt stenosis may develop and is a life threatening complication. We report on our experience in patients with Sano shunt obstruction.
Eight infants presenting with decreasing transcutaneous oxygen saturations (43-63%, median 58%) following modified Norwood procedures were shown to have relevant Sano shunt stenosis. None was suited for early stage two surgery (cavopulmonary Glenn anastomosis). Catheterization was performed at the age of 21 to 112 (median 85) days. Weight was 3.9 to 6.0 (median 4.8) kg.
Femoral 5F venous access. Long sheaths were not used. The shunt was entered with a 4F right Judkins catheter and a selective angiography was performed. The stenosis was localized proximal in 5, distal in 1 and proximal and distal in 2 patients. Ten coronary stents were implanted.
There were no procedure related complications. Oxygen saturation increased immediately to 75-86% (median 80%) and remained above 70% during follow-up in all. Seven patients had successful stage two surgery 61-288 (median 134) days after stent implantation, one is awaiting this.
Sano shunt obstruction can be treated safely and effectively by stent implantation. Early in-stent restenosis does not seem to be a problem.
置于右心室与肺动脉之间的分流管,称为Sano分流管,最近改良了用于左心发育不全综合征的诺伍德手术。接受Sano分流管治疗的患者往往更稳定,从而降低了这种仍具有挑战性的复杂心脏异常的二期手术死亡率。然而,Sano分流管狭窄可能会发生,这是一种危及生命的并发症。我们报告了我们在Sano分流管梗阻患者中的经验。
8名婴儿在接受改良诺伍德手术后经皮血氧饱和度下降(43%-63%,中位数58%),显示存在相关的Sano分流管狭窄。无一例适合早期二期手术(腔肺分流格伦吻合术)。在21至112天(中位数85天)时进行了心导管检查。体重为3.9至6.0千克(中位数4.8千克)。
经股静脉5F穿刺置管。未使用长鞘管。用4F右Judkins导管进入分流管并进行选择性血管造影。狭窄部位在近端的有5例,在远端的有1例,在近端和远端的有2例。植入了10枚冠状动脉支架。
没有与手术相关的并发症。血氧饱和度立即升至75%-86%(中位数80%),随访期间所有患者均保持在70%以上。7例患者在支架植入后61至288天(中位数134天)成功进行了二期手术,1例正在等待手术。
Sano分流管梗阻可以通过支架植入安全有效地治疗。早期支架内再狭窄似乎不是问题。