Koutinas Alexander F, Saridomichelakis Manolis N, Argyroudis Stamatis, Koutinas Christos K, Karatzanos Panagiotis, Giadinis Nektarios
Companion Animal Clinic (Medicine), Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, St. Voutyra 11, 54327, Thessaloniki, Greece.
Vet Dermatol. 2007 Aug;18(4):211-6. doi: 10.1111/j.1365-3164.2007.00593.x.
In a flock of 290 sheep, a total of 20 ewes (6.9%) with an age range of 1.5-4 years, developed a nonpruritic dermatitis characterized by alopecia/hypotrichosis, erythema, hyperpigmentation, crusting, superficial ulcers, exudation and thickening of the skin that was localized mainly to the peri-ocular area. Frequent and massive feeding of swarming sucking flies on the lesional sites was witnessed. In every instance (n = 6), Staphylococcus aureus was cultured from the exudate and the aseptically obtained skin biopsy samples from both recurrent and new cases. The main predisposing factor was the presence of small troughs, which forced the sheep to compete for food. Intramuscular administration of cefalexin for 7 days resulted in the resolution of lesions over a 2-week period. No further cases or recurrences were seen over the 16-month follow-up period. The main histopathological feature of this skin disease was a superficial and deep, perivascular to interstitial eosinophilic and mononuclear dermatitis.
在一群290只绵羊中,共有20只年龄在1.5至4岁之间的母羊(6.9%)患上了一种非瘙痒性皮肤病,其特征为脱毛/毛发稀疏、红斑、色素沉着、结痂、浅表溃疡、渗出以及皮肤增厚,主要局限于眼周区域。可见成群的吸血蝇频繁大量地叮咬病变部位。在每一个病例(n = 6)中,从复发和新发病例的渗出液以及无菌获取的皮肤活检样本中均培养出了金黄色葡萄球菌。主要的诱发因素是存在小食槽,这迫使绵羊为食物而竞争。肌肉注射头孢氨苄7天,在2周内病变得以消退。在16个月的随访期内未再出现新病例或复发情况。这种皮肤病的主要组织病理学特征是一种浅表和深部的、从血管周围到间质的嗜酸性和单核细胞性皮炎。