Smolka G, Kulach A, Dabek J, Szulc A, Gasior Z
Department of Cardiology, Medical University of Silesia, Katowice, Poland.
Haemophilia. 2007 Jul;13(4):428-31. doi: 10.1111/j.1365-2516.2007.01436.x.
The prevalence of coronary artery disease (CAD) and acute coronary syndromes in patients with haemophilia is much lower than in general population and there is a lack of information regarding safe interventional or surgical treatment of CAD in haemophiliacs. This report presents a case of patient with moderate haemophilia A and unstable angina pectoris, who underwent successful coronary angioplasty. The patient was pretreated with factor VIII (before and after the procedure) and the incision site was sealed with vessel closure device. Additionally, the article discusses the issue of the safety of standard, postpercutaneous coronary intervention antiplatelet therapy in patients with haemophilia.
血友病患者中冠状动脉疾病（CAD）和急性冠状动脉综合征的患病率远低于普通人群，并且缺乏关于血友病患者CAD安全介入或手术治疗的信息。本报告介绍了一例中度甲型血友病合并不稳定型心绞痛患者成功接受冠状动脉成形术的病例。该患者在手术前后接受了凝血因子VIII预处理，切口部位使用血管闭合装置进行封闭。此外，本文还讨论了血友病患者经皮冠状动脉介入术后标准抗血小板治疗的安全性问题。
