Nagamine Mitsue, Matsuoka Yutaka, Mori Etsuro, Fujimori Maiko, Imoto Shigeru, Kim Yoshiharu, Uchitomi Yosuke
Division of Adult Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Psychiatry Clin Neurosci. 2007 Aug;61(4):441-3. doi: 10.1111/j.1440-1819.2007.01677.x.
Considerable evidence suggests that the adrenergic system plays an important role in the biological mechanism of post-traumatic stress disorder (PTSD). In the present pilot study the association between heart rate (HR) recorded prior to slide viewing and long-term emotional memory was compared between human subjects with a past history of PTSD (n = 6) and healthy women controls (n = 12). The correlation between HR during the anticipatory period and emotional memory was significant for the PTSD group (r = 0.93, P < 0.001) but not for the control group (r = 0.21, NS). The adrenergic reaction appears to be associated with emotional memory, which may be strengthened in subjects with a past history of PTSD.
大量证据表明，肾上腺素能系统在创伤后应激障碍（PTSD）的生物学机制中起重要作用。在本初步研究中，比较了有PTSD病史的人类受试者（n = 6）和健康女性对照组（n = 12）在观看幻灯片之前记录的心率（HR）与长期情绪记忆之间的关联。PTSD组预期期的HR与情绪记忆之间的相关性显著（r = 0.93，P < 0.001），而对照组则不显著（r = 0.21，无统计学意义）。肾上腺素能反应似乎与情绪记忆有关，这在有PTSD病史的受试者中可能会增强。
