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湿化治疗哮吼无效:为何医生仍坚持使用未经证实的方法?

Lack of efficacy of humidification in the treatment of croup: Why do physicians persist in using an unproven modality?

机构信息

Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

出版信息

CJEM. 2001 Jul;3(3):209-12. doi: 10.1017/s1481803500005571.

DOI:10.1017/s1481803500005571
PMID:17610786
Abstract

BACKGROUND

Humidification is a time-honoured therapy for childhood croup (acute laryngotracheobronchitis). Despite a paucity of evidence supporting its use, many physicians, nurses and parents still apply this treatment. Our objective was to summarize available evidence and assess the rationale for the ongoing use of humidity to treat childhood croup.

METHODS

Searches of both MEDLINE and the Cochrane Database were conducted for English-language original or review literature on the treatment of croup with humidity, for the years 1966-1999.

RESULTS

Only 2 published studies have attempted to evaluate humidification therapy for croup, and none has been published since 1984. There is no published evidence to support the commonly held empirical view that humidity helps alleviate the symptoms of childhood croup, and no understanding of which factors of moisture or temperature affect patient outcomes. Risks may include scalding and unnecessary discomfort.

INTERPRETATION

There is no strong evidence supporting the use of humidity in the treatment of croup. Although such treatment is still widely used, it is not without risk, and further trials are required to address its efficacy.

摘要

背景

湿化疗法是治疗儿童急性声门下喉气管支气管炎(哮吼)的传统方法。尽管缺乏支持其应用的证据,但许多医生、护士和家长仍在使用这种治疗方法。我们的目的是总结现有证据,并评估持续使用湿度治疗儿童哮吼的合理性。

方法

对 MEDLINE 和 Cochrane 数据库进行了检索,以查找 1966 年至 1999 年间关于湿度治疗哮吼的英文原始文献或综述文献。

结果

仅有 2 项已发表的研究尝试评估湿化疗法治疗哮吼的效果,且自 1984 年以来尚无新的研究发表。没有发表的证据支持湿化疗法有助于缓解儿童哮吼症状的普遍经验观点,也不了解湿度和温度的哪些因素会影响患者的结局。风险可能包括烫伤和不必要的不适。

结论

没有强有力的证据支持在哮吼治疗中使用湿度。尽管这种治疗方法仍被广泛应用,但它并非没有风险,需要进一步的试验来确定其疗效。

相似文献

1
Lack of efficacy of humidification in the treatment of croup: Why do physicians persist in using an unproven modality?湿化治疗哮吼无效:为何医生仍坚持使用未经证实的方法?
CJEM. 2001 Jul;3(3):209-12. doi: 10.1017/s1481803500005571.
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Humidified air inhalation for treating croup: a systematic review and meta-analysis.
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Humidification in viral croup: a controlled trial.病毒性喉炎的湿化治疗:一项对照试验。
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Treatment of croup. A critical review.哮吼的治疗。一项批判性综述。
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Therapeutic air humidification; its rationale in acute laryngotracheobronchitis in children.治疗性空气加湿;其在儿童急性喉气管支气管炎中的理论依据。
AMA Arch Otolaryngol. 1955 Nov;62(5):471-7. doi: 10.1001/archotol.1955.03830050013003.
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Glucocorticoids for croup in children.用于儿童哮吼的糖皮质激素。
Cochrane Database Syst Rev. 2018 Aug 22;8(8):CD001955. doi: 10.1002/14651858.CD001955.pub4.
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Croup in the paediatric emergency department.小儿急诊科的哮吼
Paediatr Child Health. 2007 Jul;12(6):473-477. doi: 10.1093/pch/12.6.473.
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Croup.哮吼
Lancet. 2008 Jan 26;371(9609):329-39. doi: 10.1016/S0140-6736(08)60170-1.
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A cluster randomized controlled trial comparing three methods of disseminating practice guidelines for children with croup [ISRCTN73394937].一项整群随机对照试验,比较三种为患有哮吼的儿童传播实践指南的方法[国际标准随机对照试验编号73394937]
Implement Sci. 2006 Apr 28;1:10. doi: 10.1186/1748-5908-1-10.