Gioanni H, Palacios A, Sansonetti A, Varela F
Institut des Neurosciences, CNRS, Université Pierre et Marie Curie, Paris, France.
Exp Brain Res. 1991;86(3):601-7. doi: 10.1007/BF00230533.
Several functions have been proposed for the avian GLv (color vision, pupillary reflex, optomotor mechanisms). In the present paper we have examined the role of the GLv in optomotor responses. For this purpose, horizontal and vertical optokinetic nystagmus (OKN) were quantified in response to different stimulation velocities, before and after chemical (kainic acid) lesions. Unilateral lesion of the GLv produced a marked increase of the horizontal OKN gain when the eye contralateral to the lesion was stimulated in the temporonasal (T-N) direction and, to a lesser extent, when the ipsilateral eye was stimulated in the naso-temporal (N-T) direction. Biocular integration was reduced after the lesion, since the biocular stimulation corresponding to these two monocular stimulations (ipsiversive to the lesion) produced only a moderate gain increase. When stimulations were delivered in the opposite direction (contraversive to the lesion), the horizontal OKN gain was slightly increased for the N-T monocular stimulation of the eye contralateral to the lesion, but was unchanged for other stimulations. A bilateral lesion of the GLv provoked only a slight increase of the horizontal OKN gain. The vertical OKN was not affected by the GLv lesions. Thus, the GLv system is probably involved in the modulation of optomotor responses and could mediate visuo-optokinetic interactions, each nucleus (and its associated system) exerting an inhibitory (or disfacilitatory) effect on the horizontal OKN in one direction.
关于鸟类视叶峡核（GLv）已经提出了几种功能（颜色视觉、瞳孔反射、视动机制）。在本文中，我们研究了GLv在视动反应中的作用。为此，在化学（ kainic acid）损伤前后，对不同刺激速度下的水平和垂直视动性眼震（OKN）进行了量化。GLv的单侧损伤在损伤对侧眼向颞鼻（T-N）方向刺激时，水平OKN增益显著增加，在较小程度上，当同侧眼向鼻颞（N-T）方向刺激时也会增加。损伤后双眼整合减少，因为对应于这两种单眼刺激（向损伤侧同向）的双眼刺激仅产生适度的增益增加。当刺激以相反方向（与损伤侧反向）进行时，损伤对侧眼的N-T单眼刺激时水平OKN增益略有增加，但其他刺激时无变化。GLv的双侧损伤仅引起水平OKN增益的轻微增加。垂直OKN不受GLv损伤的影响。因此，GLv系统可能参与视动反应的调节，并可能介导视觉-视动相互作用，每个核（及其相关系统）在一个方向上对水平OKN发挥抑制（或去易化）作用。
