Department of Cardiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Neth Heart J. 2007 May;15(5):191-5. doi: 10.1007/BF03085979.
Coronary tortuosity is a phenomenon often encountered by cardiologists performing coronary angiography. The aetiology and clinical importance of coronary tortuosity are still unclear. Coronary tortuosity without fixed atherosclerotic stenosis in patients with angina pectoris and an abnormal exercise stress test has never been described in the literature.This article describes three cases of patients with anginal complaints, an abnormal exercise stress test and coronary angiography without the presence of a fixed atherosclerotic lesion.It is hypothesised that coronary tortuosity leads to flow alteration resulting in a reduction in coronary pressure distal to the tortuous segment of the coronary artery, subsequently leading to ischaemia. Future studies will be necessary to elucidate the actual mechanism of coronary tortuosity and its clinical significance. (Neth Heart J 2007;15:191-5.).
冠状动脉迂曲是行冠状动脉造影术的心脏病医生经常遇到的现象。冠状动脉迂曲的病因学和临床重要性仍不清楚。在心绞痛患者中,没有固定的动脉粥样硬化狭窄,且运动负荷试验异常,而冠状动脉迂曲的情况在文献中从未描述过。本文描述了 3 例胸痛、运动负荷试验异常且冠状动脉造影未见固定动脉粥样硬化病变的患者。据推测,冠状动脉迂曲导致血流改变,从而导致冠状动脉迂曲段远端的冠状动脉压力降低,随后导致缺血。未来的研究将有必要阐明冠状动脉迂曲的确切机制及其临床意义。(Neth Heart J 2007;15:191-5.)。