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ESCAPE-HCM 研究：肥厚型心肌病无症状患者筛查评估。

ESCAPE-HCM study: Evaluation of SCreening of Asymptomatic PatiEnts with Hypertrophic CardioMyopathy.

机构信息

Department of Clinical Genetics, Academic Medical Centre, Amsterdam, the Netherlands.

出版信息

Neth Heart J. 2007;15(6):216-20. doi: 10.1007/BF03085983.

DOI:10.1007/BF03085983
PMID:17612686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1896144/
Abstract

The ESCAPE-HCM study is a prospective followup study of asymptomatic mutation-carrying relatives of HCM patients aiming at optimising anamnestic and cardiological evaluation and surveillance for this group. All relatives undergo regular cardiological evaluation and risk status is prospectively estimated, according to known HCM-related risk factors for sudden cardiac death. (Neth Heart J 2007;15:216-20.).

摘要

ESCAPE-HCM 研究是一项针对肥厚型心肌病（HCM）患者无症状突变携带者的前瞻性随访研究，旨在优化该人群的病史和心血管评估及监测。所有亲属均接受定期心血管评估，并根据已知与 HCM 相关的心脏性猝死风险因素，前瞻性评估其风险状况。（Neth Heart J 2007；15：216-20.）

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本文引用的文献

1
GENCOR: a national registry for patients and families suffering from a familial heart disease in the Netherlands.GENCOR：荷兰一个针对患有家族性心脏病的患者及其家庭的全国性登记机构。
Neth Heart J. 2006 Aug;14(7-8):272-276.
2
Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study.社区中的单基因突变与左心室壁厚度增加：弗雷明汉心脏研究
Circulation. 2006 Jun 13;113(23):2697-705. doi: 10.1161/CIRCULATIONAHA.105.593558. Epub 2006 Jun 5.
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Family and population strategies for screening and counselling of inherited cardiac arrhythmias.遗传性心律失常筛查与咨询的家庭及人群策略
Ann Med. 2004;36 Suppl 1:116-24. doi: 10.1080/17431380410032526.
4
Prevalence of idiopathic hypertrophic cardiomyopathy in China: a population-based echocardiographic analysis of 8080 adults.中国特发性肥厚型心肌病的患病率：基于人群的8080例成年人超声心动图分析
Am J Med. 2004 Jan 1;116(1):14-8. doi: 10.1016/j.amjmed.2003.05.009.
5
American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines.美国心脏病学会/欧洲心脏病学会关于肥厚型心肌病的临床专家共识文件。美国心脏病学会基金会临床专家共识文件特别工作组及欧洲心脏病学会实践指南委员会的报告。
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6
The 2373insG mutation in the MYBPC3 gene is a founder mutation, which accounts for nearly one-fourth of the HCM cases in the Netherlands.
Eur Heart J. 2003 Oct;24(20):1848-53. doi: 10.1016/s0195-668x(03)00466-4.
7
Clinical course of hypertrophic cardiomyopathy with survival to advanced age.肥厚型心肌病至高龄阶段的临床病程
J Am Coll Cardiol. 2003 Sep 3;42(5):882-8. doi: 10.1016/s0735-1097(03)00855-6.
8
Risk stratification in hypertrophic cardiomyopathy: fact or fiction?肥厚型心肌病的风险分层：事实还是虚构？
J Am Coll Cardiol. 2003 Sep 3;42(5):880-1. doi: 10.1016/s0735-1097(03)00838-6.
9
Contemporary considerations for risk stratification, sudden death and prevention in hypertrophic cardiomyopathy.肥厚型心肌病风险分层、猝死及预防的当代考量
Heart. 2003 Sep;89(9):977-8. doi: 10.1136/heart.89.9.977.
10
[Hypertrophic cardiomyopathy: a genetically-carried heart disease].
Ned Tijdschr Geneeskd. 2002 Apr 13;146(15):705-12.