Morris Luc G, Tate Barbara A
Division of Sleep Medicine & Surgery, Department of Otolaryngology, New York University School of Medicine, New York, USA.
Chronobiol Int. 2007;24(3):407-11. doi: 10.1080/07420520701420352.
The degu (Octodon degus) is a diurnal rodent, although phase inversions to nocturnal behavior have been reported under specific laboratory conditions. The reliability of this animal as a diurnal model of sleep therefore requires further characterization of intrinsic circadian pacemaker properties. A phase response curve to light has been reported in the degu, and is consistent with other diurnal animals. This study reports a phase response curve to melatonin in the degu, which is distinct in orientation from the light curve.
八齿鼠（Octodon degus）是一种昼行性啮齿动物，不过在特定实验室条件下也曾有过转变为夜行性的行为报道。因此，将这种动物作为睡眠昼行模型的可靠性需要对其内在昼夜节律起搏器特性进行进一步的表征。八齿鼠的光相位反应曲线已有报道，且与其他昼行性动物一致。本研究报道了八齿鼠的褪黑素相位反应曲线，其方向与光反应曲线不同。
