Nawabi D H, Sinisi M
Peripheral Nerve Injury Unit, The Royal National, Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, HA7 4LP, UK.
J Bone Joint Surg Br. 2007 Jun;89(6):814-6. doi: 10.1302/0301-620X.89B6.19077.
Schwannomas are the most common tumours of the sheath of peripheral nerves. The clinical diagnosis is usually straightforward, but may be delayed for many years in a schwannoma of the posterior tibial nerve. The symptoms are often attributed to entrapment neuropathy or to lumbosacral radiculopathy. We describe 25 patients with a schwannoma of the posterior tibial nerve. Only three were diagnosed within a year of presentation. The mean time to diagnosis was 86.5 months with a median of 48 months (2 to 360). All the patients complained of pain, which was felt specifically in the sole of the foot in 18. A Tinel sign was detected in all 25 patients. MRI confirmed the diagnosis in all the cases in which it had been undertaken. Surgical resection of the lesion abolished the neuropathic pain. In patients with a long history of neuropathic pain in the lower limb in whom lumbar and pelvic lesions have been excluded, a benign tumour of the sheath of a peripheral nerve may explain the symptoms. Surgical resection of the tumour is safe and effective.
施万细胞瘤是周围神经鞘最常见的肿瘤。临床诊断通常很直接,但胫后神经的施万细胞瘤可能会延迟多年才被诊断出来。症状常被归因于卡压性神经病或腰骶神经根病。我们描述了25例胫后神经施万细胞瘤患者。只有3例在就诊后一年内被诊断出来。诊断的平均时间为86.5个月,中位数为48个月(2至360个月)。所有患者均主诉疼痛,其中18例疼痛具体位于足底。所有25例患者均检测到Tinel征。在所有进行MRI检查的病例中均证实了诊断。手术切除病变消除了神经性疼痛。对于有下肢神经性疼痛病史且已排除腰椎和骨盆病变的患者,周围神经鞘的良性肿瘤可能是症状的原因。手术切除肿瘤安全有效。