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胫神经周围神经鞘瘤:一组病例的手术结果

Peripheral schwannomas of the tibial nerve: surgical results in a case series.

作者信息

Andreani Lorenzo, Ipponi Edoardo, Ruinato Alfio Damiano, Falcinelli Federico, De Franco Silvia, D'Arienzo Antonio, Capanna Rodolfo

机构信息

Department of Orthopaedic and Trauma Surgery, University of Pisa, Pisa, Italy.

Department of Orthopedic and Trauma Surgery, University of Pisa, Pisa, Italy.

出版信息

Acta Biomed. 2022 Mar 14;93(1):e2022085. doi: 10.23750/abm.v93i1.11782.

Abstract

BACKGROUND AND AIM OF THE WORK

Schwannomas of the lower limb are uncommon benign tumors and those arising from Tibial Nerve are particularly rare. We report our experience on the topic, with particular attention to clinical presentation and lower limbs overall functionality before and after treatment. Our aim is to assess clinical impairment caused by the tumor and evaluate the effectiveness of surgical treatment.

MATERIALS AND METHODS

Time between symptoms outbreak and diagnosis, as well as pre- operative tumor size were evaluated for each case. Pre-operative and post-operative overall lower limb functionality were assessed using both MSTS and LEFS scores. Sensitive symptoms and muscular strength were also evaluated before and after surgery.

RESULTS

7 patients were included in our study. The mean follow-up was 22.9 months. Average diagnostic delay was 8 months and tumor size was 29.3mm. Before surgery each patient had positive Hoffmann-Tinel sign and an at least mild paresthesia, 57% of our cases had slight reduction of muscular strength. Pre-operative MSTS score was 24.4 and LEFS score was 64.7. Tumor size and diagnostic delay were associated with pre-operative functionality. No major local complication was recorded during or after surgery. Each patient with pre-operative sensitive or motorial deficit benefited the effects of surgical treatment.

CONCLUSIONS

Our cases suggest early diagnosis could reduce the impact of the disease on patients' activities of daily living and quality of life. Surgery, for its part, represents a safe and reliable approach to Tibial Nerve schwannomas with good chances of clinical and functional remission.

摘要

工作背景与目的

下肢神经鞘瘤是一种罕见的良性肿瘤,起源于胫神经的神经鞘瘤尤为罕见。我们报告了在该主题方面的经验,特别关注治疗前后的临床表现及下肢整体功能。我们的目的是评估肿瘤所致的临床损伤,并评价手术治疗的效果。

材料与方法

评估每例患者症状出现至诊断的时间以及术前肿瘤大小。使用肌肉骨骼肿瘤学会(MSTS)评分和下肢功能评分(LEFS)评估术前及术后下肢整体功能。还评估了手术前后的敏感症状及肌肉力量。

结果

我们的研究纳入了7例患者。平均随访时间为22.9个月。平均诊断延迟为8个月,肿瘤大小为29.3毫米。术前,每位患者的霍夫曼征均为阳性,且至少有轻度感觉异常,57%的病例肌肉力量略有下降。术前MSTS评分为24.4,LEFS评分为64.7。肿瘤大小和诊断延迟与术前功能相关。手术期间及术后未记录到严重的局部并发症。每位术前有感觉或运动功能障碍的患者都从手术治疗中获益。

结论

我们的病例表明,早期诊断可减少疾病对患者日常生活活动及生活质量的影响。就手术而言,它是治疗胫神经鞘瘤的一种安全可靠的方法,临床及功能缓解的机会较大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/8972880/4535153f4330/ACTA-93-85-g001.jpg

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