Toussaint Ariane, Lima-Mendez Gipsi, Leplae Raphaël
Service de Conformation de Macromolécules Biologiques et de Bioinformatique, Université Libre de Bruxelles, ULB, Bvd du Triomphe, Campus Plaine - CP 263, B1050 Bruxelles, Belgium.
Res Microbiol. 2007 Sep;158(7):567-71. doi: 10.1016/j.resmic.2007.05.002. Epub 2007 May 21.
As is the case for other genomes and metagenomes, complete nucleotide sequences of bacteriophages and archaeviruses have become increasingly numerous and require robust annotation tools. We present here the first version of a phage ontology, PhiGO, which should contribute to more informational annotation of gene products in phage and prophage sequences. PhiGO uses the Gene Ontology schema, the de facto standard for describing knowledge about gene products across many databases.
与其他基因组和宏基因组的情况一样,噬菌体和古病毒的完整核苷酸序列越来越多,需要强大的注释工具。我们在此展示噬菌体本体(PhiGO)的首个版本,它应有助于对噬菌体和原噬菌体序列中的基因产物进行更具信息性的注释。PhiGO使用基因本体模式,这是跨多个数据库描述基因产物知识的事实上的标准。