Wessman Dylan E, Kim Thu-Thuy T, Parrish John S
Department of Internal Medicine, Naval Medical Center San Diego, San Diego, CA 92134, USA.
Mil Med. 2007 Jun;172(6):666-8. doi: 10.7205/milmed.172.6.666.
An active duty male presented to the emergency room with dyspnea for 2 days after undergoing liposuction surgery. Upon presentation, the patient was afebrile, tachycardic, tachypneic, and hypoxemic. The initial chest radiograph demonstrated bilateral patchy opacities and the PaO2/FiO2 ratio was <200. The patient was admitted to the medical intensive care unit for supportive care. He was treated empirically for pneumonia. Blood and sputum cultures were negative. A computed tomography angiogram of the chest was negative for pulmonary embolism but did reveal a bilateral, perihilar air space process. The patient's oxygen requirement improved and the abnormal chest radiographic findings resolved over the next 48 hours. Given his clinical presentation, negative workup, and rapid recovery, the patient was given a presumptive diagnosis of pulmonary fat embolism. Fat embolism occurs when adipocytes and small blood vessels are damaged during the liposuction procedure. Patients may present with low-grade fever, tachycardia, tachypnea, hypoxemia, and hypocapnia. The differential diagnosis includes venous thromboembolism, aspiration pneumonitis, and pneumonia. The mainstay of treatment for pulmonary fat embolism is supportive care. The risk of mortality is 5 to 15%.
一名现役男性在接受抽脂手术后因呼吸困难两天就诊于急诊室。就诊时,患者无发热,心动过速,呼吸急促,且低氧血症。初始胸部X光片显示双侧斑片状模糊影,动脉血氧分压/吸入氧分数值<200。患者被收入医疗重症监护病房进行支持治疗。对其进行了经验性肺炎治疗。血培养和痰培养均为阴性。胸部计算机断层血管造影未发现肺栓塞,但确实显示双侧肺门周围气腔病变。患者的氧气需求在接下来的48小时内有所改善,胸部X光异常表现也消失了。鉴于其临床表现、检查结果阴性及恢复迅速,该患者被初步诊断为肺脂肪栓塞。脂肪栓塞发生于抽脂手术过程中脂肪细胞和小血管受损时。患者可能出现低热、心动过速、呼吸急促、低氧血症和低碳酸血症。鉴别诊断包括静脉血栓栓塞、吸入性肺炎和肺炎。肺脂肪栓塞的主要治疗方法是支持治疗。死亡率为5%至15%。