Christensen Dale B, Roth Mary, Trygstad Troy, Byrd John
Division of Pharmaceutical Outcomes and Policy, School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599-7360, USA.
J Am Pharm Assoc (2003). 2007 Jul-Aug;47(4):471-83. doi: 10.1331/JAPhA.2007.06111.
To assess the feasibility of a pharmacist-based medication therapy management (MTM) service for North Carolina State Health Plan enrollees.
Before/after design with two control groups.
Community pharmacies and an ambulatory care clinic in North Carolina serving patients from October 2004 to March 2005.
67 patients who used a large number of prescription drugs, 10 community/ambulatory care pharmacists, and more than 600 participants from two control groups.
Pharmacist-conducted MTM reviews for volunteering patients.
Process measures (type and frequency of drug therapy problems detected and services performed), economic measures (number and cost of medications dispensed), and humanistic measures (patient satisfaction with services).
Pharmacists identified an average of 3.6 potential drug therapy problems (PDTPs) per patient at the first visit. The most common PDTP categories were "potential underuse" and "more cost-effective drug available." Pharmacist actions were divided nearly equally between activities that would result in increased and decreased drug use. Pharmacists recommended a drug therapy change in about 50% of patients and contacted the prescriber more than 85% of the time. About 50% of patients with PDTPs had a change in drug therapy. Prescription use during the postintervention period decreased in both the study and control groups but was statistically significant only among the control groups. No significant differences were observed in patient co-payment or insurer prescription costs. Pharmacists provided the following educational services: medication use (90%), disease management (88%), adherence, and self-care (60%). Survey results indicated that patients highly valued the service.
A voluntary MTM program targeted at ambulatory patients using a large number of medications reduced the number of PDTPs but did not necessarily result in reductions in prescription drug use or cost. Nearly all patients received some form of medication adherence or disease education associated with problem detection and resolution. Patient satisfaction levels with the service were very high.
评估为北卡罗来纳州健康计划参保者提供的基于药剂师的药物治疗管理(MTM)服务的可行性。
设有两个对照组的前后对照设计。
北卡罗来纳州的社区药房和一家门诊护理诊所,于2004年10月至2005年3月为患者服务。
67名使用大量处方药的患者、10名社区/门诊护理药剂师以及来自两个对照组的600多名参与者。
药剂师为自愿参与的患者进行MTM评估。
过程指标(检测到的药物治疗问题类型和频率以及提供的服务)、经济指标(配药数量和成本)以及人文指标(患者对服务的满意度)。
药剂师在首次就诊时平均为每位患者识别出3.6个潜在药物治疗问题(PDTPs)。最常见的PDTP类别是“潜在用药不足”和“有更具成本效益的药物可用”。药剂师的行动在会导致用药增加和减少的活动之间几乎平均分配。药剂师在约50%的患者中建议了药物治疗变更,并且超过85%的情况下联系了开处方者。约50%有PDTPs的患者进行了药物治疗变更。干预后期间,研究组和对照组的处方使用均有所下降,但仅在对照组中具有统计学意义。患者自付费用或保险公司的处方成本未观察到显著差异。药剂师提供了以下教育服务:用药(90%)、疾病管理(88%)、依从性和自我护理(60%)。调查结果表明患者对该服务评价很高。
针对使用大量药物的门诊患者的自愿MTM项目减少了PDTPs的数量,但不一定导致处方药使用或成本的降低。几乎所有患者都接受了与问题检测和解决相关的某种形式的用药依从性或疾病教育。患者对该服务的满意度非常高。