Suppr超能文献

评估在社区药房环境中开展药物遗传学检测的可行性。

Assessing feasibility of delivering pharmacogenetic testing in a community pharmacy setting.

作者信息

Haga Susanne B, Moaddeb Jivan, Mills Rachel, Voora Deepak

机构信息

Center for Applied Genomics & Precision Medicine, Duke University School of Medicine, 304 Research Drive, Box 90141, Durham, NC 27708, USA.

出版信息

Pharmacogenomics. 2017 Mar;18(4):327-335. doi: 10.2217/pgs-2016-0175. Epub 2017 Feb 22.

Abstract

AIM

To describe the rationale and design of a study evaluating the delivery of pharmacogenetic (PGx) testing in community pharmacies. Study rationale: Pharmacists have expressed interest in offering PGx testing; however, their lack of knowledge and experience, patients' acceptance and feasibility are unknown in this setting.

STUDY DESIGN

Through a cluster randomized trial, we will assess pharmacist and patient experiences with delivery of PGx testing as a standalone service or integrated into medication therapy management services. Anticipated results: We anticipate that PGx testing can be delivered in a community pharmacy setting and accepted and valued by patients.

CONCLUSION

This study is expected to provide valuable evidence about the real-world feasibility and acceptance of a community pharmacist-delivered approach of PGx testing.

摘要

目的

描述一项评估社区药房药物遗传学(PGx)检测服务的原理及设计。研究原理:药剂师已表示有兴趣提供PGx检测;然而,在此环境下,他们知识和经验的欠缺、患者的接受度以及可行性尚不清楚。

研究设计

通过一项整群随机试验,我们将评估药剂师和患者在接受PGx检测作为一项独立服务或整合到药物治疗管理服务中的体验。预期结果:我们预计PGx检测可在社区药房环境中提供,并为患者所接受和重视。

结论

本研究有望提供关于社区药剂师提供PGx检测方法在现实世界中的可行性和接受度的宝贵证据。

相似文献

1
Assessing feasibility of delivering pharmacogenetic testing in a community pharmacy setting.
Pharmacogenomics. 2017 Mar;18(4):327-335. doi: 10.2217/pgs-2016-0175. Epub 2017 Feb 22.
2
Community pharmacists' experience with pharmacogenetic testing.
J Am Pharm Assoc (2003). 2015 Nov-Dec;55(6):587-594. doi: 10.1331/JAPhA.2015.15017.
3
Independent Community Pharmacists' Experience in Offering Pharmacogenetic Testing.
Pharmgenomics Pers Med. 2021 Jul 15;14:877-886. doi: 10.2147/PGPM.S314972. eCollection 2021.
4
Mapping the implementation of pharmacogenomic testing in community pharmacies 2003-2021 using the Theoretical Domains Framework: A scoping review.
J Am Pharm Assoc (2003). 2023 Mar-Apr;63(2):459-476.e6. doi: 10.1016/j.japh.2022.09.019. Epub 2022 Sep 28.
5
The Innovative Canadian Pharmacogenomic Screening Initiative in Community Pharmacy (ICANPIC) study.
J Am Pharm Assoc (2003). 2017 Sep-Oct;57(5):624-629. doi: 10.1016/j.japh.2017.05.006. Epub 2017 Jul 6.
6
Pilot study: incorporation of pharmacogenetic testing in medication therapy management services.
Pharmacogenomics. 2014 Nov;15(14):1729-1737. doi: 10.2217/pgs.14.118.
7
Pharmacogenetic testing and counselling in the community pharmacy: mixed-methods study of a new pharmacist-led service.
Int J Clin Pharm. 2023 Dec;45(6):1378-1386. doi: 10.1007/s11096-023-01596-8. Epub 2023 Jun 20.
8
Delivery of Pharmacogenetic Testing with or without Medication Therapy Management in a Community Pharmacy Setting.
Pharmgenomics Pers Med. 2021 Jul 9;14:785-796. doi: 10.2147/PGPM.S314961. eCollection 2021.
9
Implementation of a pharmacogenomics service in a community pharmacy.
J Am Pharm Assoc (2003). 2014 Mar-Apr;54(2):172-80. doi: 10.1331/JAPhA.2014.13033.
10
Pilot study of pharmacist-assisted delivery of pharmacogenetic testing in a primary care setting.
Pharmacogenomics. 2014 Sep;15(13):1677-86. doi: 10.2217/pgs.14.109.

引用本文的文献

2
Independent Community Pharmacists' Experience in Offering Pharmacogenetic Testing.
Pharmgenomics Pers Med. 2021 Jul 15;14:877-886. doi: 10.2147/PGPM.S314972. eCollection 2021.
3
Delivery of Pharmacogenetic Testing with or without Medication Therapy Management in a Community Pharmacy Setting.
Pharmgenomics Pers Med. 2021 Jul 9;14:785-796. doi: 10.2147/PGPM.S314961. eCollection 2021.
4
Pharmacogenomics in the United States Community Pharmacy Setting: The Clopidogrel- Example.
Pharmgenomics Pers Med. 2021 May 18;14:569-577. doi: 10.2147/PGPM.S224894. eCollection 2021.
5
Community pharmacy interventions for health promotion: effects on professional practice and health outcomes.
Cochrane Database Syst Rev. 2019 Dec 6;12(12):CD011207. doi: 10.1002/14651858.CD011207.pub2.
7
Ready or not, here it comes: Direct-to-consumer pharmacogenomic testing and its implications for community pharmacists.
J Am Pharm Assoc (2003). 2019 Sep-Oct;59(5):646-650. doi: 10.1016/j.japh.2019.06.008. Epub 2019 Jul 18.
8
Interpretation of the effect of CYP2C9, VKORC1 and CYP4F2 variants on warfarin dosing adjustment in Turkey.
Mol Biol Rep. 2019 Apr;46(2):1825-1833. doi: 10.1007/s11033-019-04634-9. Epub 2019 Feb 2.

本文引用的文献

1
2
Evaluation of a pharmacogenetic educational toolkit for community pharmacists.
Pharmacogenomics. 2016 Sep;17(14):1491-502. doi: 10.2217/pgs-2016-0002. Epub 2016 Aug 17.
4
Incorporation of pharmacogenetic testing into medication therapy management.
Pharmacogenomics. 2015 Nov;16(17):1931-41. doi: 10.2217/pgs.15.124. Epub 2015 Nov 10.
5
Community pharmacists' experience with pharmacogenetic testing.
J Am Pharm Assoc (2003). 2015 Nov-Dec;55(6):587-594. doi: 10.1331/JAPhA.2015.15017.
7
Strategies for implementation of an effective pharmacogenomics program in pharmacy education.
Pharmacogenomics. 2015 Jul;16(8):905-11. doi: 10.2217/pgs.15.50. Epub 2015 Jun 12.
8
TransitionRx: Impact of community pharmacy postdischarge medication therapy management on hospital readmission rate.
J Am Pharm Assoc (2003). 2015 May-Jun;55(3):246-54. doi: 10.1331/JAPhA.2015.14060.
10
Evaluation of a shared pharmacogenomics curriculum for pharmacy students.
Pharmacogenomics. 2015;16(4):315-22. doi: 10.2217/pgs.14.181.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验