Zakheim R M, Molteni A, Mattioli L, Mullis K B
J Clin Endocrinol Metab. 1976 Mar;42(3):588-9. doi: 10.1210/jcem-42-3-588.
In 11 healthy, normotensive young women taking contraceptive medication (Enovid) for at least one year, plasma levels of angiotensin II were significantly higher than in healthy male and female controls. No significant difference was seen in the serum activity of angiotensin I-converting enzyme measured in vitro. Although serum angiotensin I converting enzyme activity is stimulated in several conditions in which other components of renin-angiotensin-aldosterone system are increased, this is not the case during administration of estrogens.
在11名服用避孕药（炔诺酮）至少一年的健康、血压正常的年轻女性中，血管紧张素II的血浆水平显著高于健康男性和女性对照组。体外测量的血管紧张素I转换酶的血清活性未见显著差异。尽管在肾素-血管紧张素-醛固酮系统的其他成分增加的几种情况下，血清血管紧张素I转换酶活性会受到刺激，但在服用雌激素期间并非如此。
